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BRENDA support

Ligand Alpha1-proteinase inhibitor

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Basic Ligand Information

Molecular Formula
BRENDA Name
InChIKey
Alpha1-proteinase inhibitor

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-
alpha1-proteinase inhibitor + H2O = ?
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
89.6% inhibition at 0.00015 mM
-
engineering of functional exosites in P1 Arg variant increases the association rate constant for the reactions with factors Xa and IXa, without affecting the inhibitor reactions with trypsin and thrombin. Mutation K222Y/L224E in alpha1-proteinase inhibitor increases the association rate constant 14fold
-
inhibits cleavage of Val-Gln-Arg-Glu-Lys-Arg-Ala-Val-Gly-Leu
-

Enzyme Kinetic Parameters

References & Links

Links to other databases for Alpha1-proteinase inhibitor

EXTERNAL LINKS