Ligand Glutaramate

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Basic Ligand Information

Molecular Structure
Picture of Glutaramate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H9NO3
Glutaramate
CANCPUBPPUIWPX-UHFFFAOYSA-N
Synonyms:
4-carboxybutyramide, glutaramic acid, glutaramide, glutarate monoamide, Glutaric acid 5-amide, glutaric acid monoamide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glutaramic acid + H2O = glutaric acid + NH3
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glutaramate + H2O = ?
show the reaction diagram
-
glutaramic acid + H2O = glutaric acid + NH3
show the reaction diagram
-
glutaramide + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glutarimide + H2O = glutaric acid monoamide
show the reaction diagram
-
cyano-5-valeramide + H2O = glutaric acid 5-amide + NH3
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
and derivatives
-
competitive inhibition, 10 mM glutaramate, hydrolysis of methyl alpha-ketoglutarate: 43% inhibition, hydrolysis of ethyl alpha-ketoglutarate: 34% inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0372
-
-

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.8
-
-

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
12.6
-
-
0.63
-
-

References & Links

Links to other databases for Glutaramate

ChEBI
PubChem
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PubChem