Ligand esculin

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Basic Ligand Information

Molecular Structure
Picture of esculin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H16O9
esculin
XHCADAYNFIFUHF-TVKJYDDYSA-N
Synonyms:
6,7-dihydroxycoumarin 6-glucoside, 7-hydroxy-2-oxo-2H-chromen-6-yl hexopyranoside, Aesculin, Bicolorin, Crataegin, Enallachrome, Escosyl, Esculetin 6-beta-D-glucoside, esculetin 6-O-beta-D-glucoside, Esculetin 6-O-glucoside, Esculine, Esculoside, Polychrom, Polychrome, Vitamin C2

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDPglucose + aesculin = UDP + 4-O-beta-D-glucosyl-aesculin
show the reaction diagram
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sucrose + aesculin = D-fructose + aesculin 4-alpha-glucoside
show the reaction diagram
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esculin + H2O = esculetin + beta-D-glucose
show the reaction diagram
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maltose + esculin = ?
show the reaction diagram
-
esculin + H2O = ?
show the reaction diagram
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aesculin + H2O = aesculetin + D-glucose
show the reaction diagram
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esculin + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-glucose + esculetin = UDP + esculetin 6-O-beta-D-glucoside
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
induces the enzyme in different organs, e.g. Malphigian tubules, midgut, fat body, hemolymph, and body wall, when feeded to larvae
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
mixed type of noncompetitive inhibition, pH 5.5, 80°C
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.24
-
pH 5.5, 30°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0043
-
pH 5.5, 80°C

References & Links

Links to other databases for esculin

ChEBI
PubChem
ChEBI
PubChem