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BRENDA support

Ligand deamino-NADH

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Basic Ligand Information

Molecular Structure
Picture of deamino-NADH (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H28N6O15P2
deamino-NADH
WXWNHSQIXJHVJY-NNYOXOHSSA-M
Synonyms:
NHDH, reduced beta-nicotinamide hypoxanthine dinucleotide, [[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)tetrahydrofuran-2-yl]methyl hydrogen phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
deamino-NADH + H+ + 2,3-dimethoxy-5-methyl-1,4-benzoquinone = deamino-NAD+ + 2,3-dimethoxy-5-methyl-1,4-benzoquinol
show the reaction diagram
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des-myo-inositol mycothione + reduced beta-nicotinamide hypoxanthine dinucleotide = ?
show the reaction diagram
-
deamino-NADH + H2O = deamino-NMNH + AMP
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-malate + deamino-NAD+ = oxaloacetate + deamino-NADH + H+
show the reaction diagram
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isocitrate + NHD+ = 2-oxoglutarate + CO2 + NHDH
show the reaction diagram
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formate + deamino-NAD+ = CO2 + deamino-NADH
show the reaction diagram
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propanal + deamino-NAD+ + H2O = propionate + deamino-NADH
show the reaction diagram
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acetaldehyde + deamino-NAD+ + H2O = acetate + deamino-NADH + H+
show the reaction diagram
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L-Ala + H2O + deamino-NAD+ = pyruvate + NH3 + deamino-NADH
show the reaction diagram
-
L-glutamate + deamino-NAD+ = L-glutamine + 2-oxoglutarate + deamino-NADH + H+
show the reaction diagram
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L-lysine + deamino-NAD+ + H2O = alpha-aminoadipate delta-semialdehyde + NH3 + deamino-NADH
show the reaction diagram
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L-Leu + H2O + deamino-NAD+ = 4-methyl-2-oxopentanoate + NH3 + deamino-NADH
show the reaction diagram
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L-erythro-3,5-diaminohexanoate + H2O + deamino-NAD+ = 5-amino-3-oxohexanoate + NH3 + deamino-NADH + H+
show the reaction diagram
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NADPH + deamino-NAD+ = NADP+ + deamino-NADH
show the reaction diagram
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NADPH + deamino-NAD+ = NADP+ + deamino-NADH
show the reaction diagram
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Enzyme Cofactor/Cosubstrate (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
as effective as NADH
-

Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
-
des-myo-inositol mycothione as second substrate
0.29
-
in presence of 20 mM MgCl2, 50 mM Tris-HCl, pH 8.5
0.0004
-
pH 8.0, 26°C

References & Links

Links to other databases for deamino-NADH

ChEBI
PubChem
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PubChem