Ligand 2,5-dioxopentanoate

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Basic Ligand Information

Molecular Structure
Picture of 2,5-dioxopentanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H6O4
2,5-dioxopentanoate
VHKNBDIQDAXGBL-UHFFFAOYSA-N
Synonyms:
2-oxo-glutarate semialdehyde, 2-oxoglutarate semialdehyde, 2-oxoglutaric semialdehyde, alpha-Ketoglutaric semialdehyde


Show all pahtways known for Show all BRENDA pathways known for 2,5-dioxopentanoate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-3-deoxy-D-arabinonate = 2,5-dioxopentanoate + H2O
show the reaction diagram
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5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-oxoglutaric semialdehyde + NAD+ + H2O = 2-oxoglutarate + NADH
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-3-deoxy-D-arabinonate = 2,5-dioxopentanoate + H2O
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (16 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2,5-dioxopentanoate

ChEBI
PubChem
ChEBI
PubChem