print visible entries

print all entries

Ligand CDP-dioleoylglycerol

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (10 results)

top print hide

Show Substrate (10 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.8.11

CDP-dioleoylglycerol + D-myo-inositol = CMP + 1,2-dioleoyl-phosphatidyl-1D-myo-inositol

690824

-

2.7.8.11

CDP-dioleoylglycerol + myo-inositol = CMP + dioleoylphosphatidylinositol

645297, 645299

-

2.7.8.41

CDP-dioleoylglycerol + 1,2-dilinoleoylphosphatidylglycerol = 1-(1-linoleoyl-2-linoleoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727509

-

2.7.8.41

CDP-dioleoylglycerol + 1,2-dimyristoylphosphatidylglycerol = 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-myristoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727509

-

2.7.8.41

CDP-dioleoylglycerol + 1,2-dioleoylphosphatidylglycerol = 1,3-bis(1,2-dioleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727054, 727509

-

2.7.8.41

CDP-dioleoylglycerol + 1,2-dipalmitoylphosphatidylglycerol = 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-palmitoyl-2-palmitoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727509

-

2.7.8.41

CDP-dioleoylglycerol + 1-oleoyl-2-linoleoyl phosphatidylglycerol = 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-oleoyl-2-linoleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727509

-

2.7.8.41

CDP-dioleoylglycerol + 1-palmitoyl-2-oleoyl phosphatidylglycerol = 1-(1-oleoyl-2-oleoyl-sn-glycero-3-phospho)-3-(1-palmitoyl-2-oleoyl-sn-glycero-3-phospho)-sn-glycerol + CMP

727509

-

2.7.8.41

CDP-dioleoylglycerol + dioleoylphosphatidylglycerol = a cardiolipin + CMP

727507

-

2.7.8.41

CDP-dioleoylglycerol + dipalmitoylphosphatidylglycerol = a cardiolipin + CMP

727507

-

2.7.8.11

2 entries

2.7.8.41

8 entries

Product in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Product (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.7.7.41

CTP + 1,2-dioleoyl phosphatidic acid = diphosphate + CDP-dioleoylglycerol

0

-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Inhibitors (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

2.7.8.41

above 0.1 mM

727054

-

Enzyme Kinetic Parameters

K_M Value (2 results)

top print hide

Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

2.7.8.41

0.0014

-

pH 8.8, 30°C

727507

2.7.8.41

0.036

-

pH 9.0, 45°C

727054

2.7.8.41

2 entries

References & Links

Literature References (6)

top print hide

Show Reference (6 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

645297

-

Properties of cytidinediphosphodiacyl-sn-glycerol:myoinositol transferase of bovine mammary tissue

1977

Wootton, J.A.; Kinsella, J.E.

Int. J. Biochem.

8

449-456

645299

41587

Characterization of the forward and reverse reactions catalyzed by CDP-diacylglycerol:inositol transferase in rabbit lung tissue

1979

Bleasdale, J.E.; Wallis, P.; MacDonald, P.C.; Johnston, J.M.

Biochim. Biophys. Acta

575

135-147

690824

18402553

Alternative metabolic fates of phosphatidylinositol produced by phosphatidylinositol synthase isoforms in Arabidopsis thaliana

2008

Loefke, C.; Ischebeck, T.; Koenig, S.; Freitag, S.; Heilmann, I.

Biochem. J.

413

115-124

727054

2171667

Biochemical characterization and regulation of cardiolipin synthase in Saccharomyces cerevisiae

1990

Tamai, K.T.; Greenberg, M.L.

Biochim. Biophys. Acta

1046

214-222

727507

15811335

Cardiolipin synthase of Arabidopsis thaliana

2005

Nowicki, M.; Müller, F.; Frentzen, M.

FEBS Lett.

579

2161-2165

727509

16678169

Identification and characterization of human cardiolipin synthase

2006

Houtkooper, R.H.; Akbari, H.; van Lenthe, H.; Kulik, W.; Wanders, R.J.; Frentzen, M.; Vaz, F.M.

FEBS Lett.

580

3059-3064

Links to other databases for CDP-dioleoylglycerol

top print hide

Show Links (1 entry)

ChEBI

PubChem

-