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Ligand 1,2-diarachidonoyl-glycerol Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C4 3 H6 8 O5
1,2-diarachidonoyl-glycerol
FVXRWZPVZULNCQ-XCHUKFSYSA-N
1,2-diarachidonoylglycerol
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (1 result)
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ATP + 1,2-diarachidonoyl-glycerol = ADP + 1,2-diarachidonoyl-glycerol 3-phosphate
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Product in Enzyme-catalyzed Reactions (1 result)
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arachidonoylphosphatidylinositol + H2O = myo-inositol 1-phosphate + 1,2-diarachidonoylglycerol
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Enzyme Kinetic Parameters
KM Value (2 results)
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0.09
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pH 7.4, 30°C, enzyme form DGK I
0.14
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pH 7.4, 30°C, enzyme form DGK IV
References & Links Literature References (2)
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Purification and characterization of membrane-bound and cytosolic forms of diacylglycerol kinase from rat brain
1990
Kato, M.; Takenawa, T.
J. Biol. Chem.
265
794-800
Aggregated beta amyloid peptide 1-40 decreases Ca2+- and cholinergic receptor-mediated phosphoinositide degradation by alteration of membrane and cytosolic phospholipase C in brain cortex
2000
Zambrzycka, A.; Strosznajder, R.P.; Strosznajder, J.B.
Neurochem. Res.
25
189-196
Links to other databases for 1,2-diarachidonoyl-glycerol