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Ligand propionyl-[acyl-carrier protein] Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 7 H3 0 N3 O9 PR2 S
propionyl-[acyl-carrier protein]
propionyl-ACP, propionyl-RifM1, propionyl-[acyl carrier protein]
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (6 results)
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propionyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = beta-ketopentanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
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propionyl-[acyl-carrier protein] + L-alanine = 1-[(4S)-4-amino-5-oxoheptyl]guanidine + CO2 + holo-[acyl-carrier protein]
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propionyl-[acyl-carrier protein] + L-arginine = N-[(4S)-4-amino-5-oxoheptyl]guanidine + CO2 + holo-[acyl-carrier protein]
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propionyl-[acyl-carrier protein] + H2O = propionate + acyl-carrier protein
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propionyl-RifM1 + H2O = ?
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propionyl-[acyl-carrier protein] + H2O = propionate + acyl-carrier protein
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Product in Enzyme-catalyzed Reactions (3 results)
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propionyl-CoA + [acyl-carrier protein] = CoA + propionyl-[acyl-carrier protein]
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propionyl-CoA + an [acyl-carrier protein] = CoA + propionyl-[acyl carrier protein]
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propionyl-CoA + acyl-carrier protein = CoA + propionyl-[acyl-carrier protein]
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Enzyme Kinetic Parameters
References & Links Literature References (5)
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Studies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier protein-condensing enzyme from Escherichia coli
1966
Toomey, R.E.; Wakil, S.J.
J. Biol. Chem.
241
1159-1165
Purification and properties of the Streptomyces peucetius DpsC beta-ketoacyl:acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis
1999
Bao, W.; Sheldon, P.J.; Hutchinson, C.R.
Biochemistry
38
9752-9757
Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin
2002
Kim, B.S.; Cropp, T.A.; Beck, B.J.; Sherman, D.H.; Reynolds, K.A.
J. Biol. Chem.
277
48028-48034
Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway
2009
Claxton, H.B.; Akey, D.L.; Silver, M.K.; Admiraal, S.J.; Smith, J.L.
J. Biol. Chem.
284
5021-5029
Biocatalytic synthesis of alpha-amino ketones
2019
Chun, S.W.; Narayan, A.R.H.
Synlett
30
1269-1274
Links to other databases for propionyl-[acyl-carrier protein]
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