Ligand amphotericin B

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Basic Ligand Information

Molecular Structure
Picture of amphotericin B (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C47H73NO17
amphotericin B
APKFDSVGJQXUKY-INPOYWNPSA-N
Synonyms:
amphotericin, amphotericine B

Show all pahtways known for Show all pathways known for amphotericin B

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
29% enhancement of activity at a concentration of 0.032 mg/ml
-
activates at concentrations below 5.4 nM, optimal at 2.1 nM, wild-type and mutant
-

Inhibitor in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.0346 mM, 100% inhibition
-
100% inhibition at a concentration of 0.032 mg/ml
-
noncompetitive
-

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.13
-
-

References & Links

Links to other databases for amphotericin B

ChEBI
PubChem
ChEBI
PubChem