Ligand (R)-3-hydroxybutyryl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (R)-3-hydroxybutyryl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C25H42N7O18P3S
(R)-3-hydroxybutyryl-CoA
QHHKKMYHDBRONY-JYMPOPDUSA-N
Synonyms:
(3R)-3-hydroxybutyryl-coenzyme A, (3R)-D-3-hydroxybutyryl-CoA, D-beta-hydroxybutyryl-CoA, D-hydroxybutyryl-CoA
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for (R)-3-hydroxybutyryl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
acetoacetyl-CoA + NADPH = D-beta-hydroxybutyryl-CoA + NADP+
-
-
show the reaction diagram
crotonyl-CoA + H2O = (R)-3-hydroxybutyryl-CoA
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
25°C, pH 7.0, mutant enzyme G4D, based on one catalytic site in a dimeric enzyme
26
-
25°C, pH 7.0, wild-type enzyme, based on one catalytic site in a dimeric enzyme
44
-
30°C, first phase of reaction
65.33
-
30°C, second phase of reaction
18.67
-
based on the assumption that 2 PhaC and 2 PhaE subunits comprise one catalytic site
320
-

KM Value (9 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
25°C, pH 7.0, mutant enzyme G4D, based on one catalytic site in a dimeric enzyme
0.32
-
25°C, pH 7.0, wild-type enzyme, based on one catalytic site in a dimeric enzyme
0.19
-
30°C, first phase of reaction
0.13
-
30°C, second phase of reaction
0.45
-

References & Links

Links to other databases for (R)-3-hydroxybutyryl-CoA

ChEBI
PubChem
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PubChem