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Ligand 3-oxooctanoyl-[acyl-carrier protein]

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for 3-oxooctanoyl-[acyl-carrier protein]

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

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Show Natural Substrate (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.184

3-oxo-octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine = [acyl-carrier protein] + S-methyl-5'-thioadenosine + 3-oxo-octanoyl-L-homoserine lactone

720492

-

2.3.1.184

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein] = 5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

665602, 665410

-

2.3.1.184

2 entries

Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Substrate (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.100

3-oxooctanoyl-[acyl-carrier protein] + NADPH = (R)-3-hydroxyoctanoyl-[acyl-carrier protein] + NADP+

763418, 763477

-

2.3.1.184

3-oxo-octanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine = [acyl-carrier protein] + S-methyl-5'-thioadenosine + 3-oxo-octanoyl-L-homoserine lactone

720492

-

2.3.1.184

S-adenosyl-L-methionine + 3-oxooctanoyl-[acyl-carrier protein] = 5'-methylthioadenosine + N-3-oxooctanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]

665602, 665410

-

2.3.1.184

2 entries

Product in Enzyme-catalyzed Reactions (2 results)

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Show Product (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.3.1.180

hexanoyl-CoA + malonyl-[acyl-carrier protein] = 3-oxo-octanoyl-[acyl-carrier protein] + CoA + CO2

0

-

2.3.1.41

hexanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxooctanoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]

0

-

Enzyme Kinetic Parameters

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

665410

16385067

Quorum-sensing signal synthesis by the Yersinia pestis acyl-homoserine lactone synthase YspI

2006

Kirwan, J.P.; Gould, T.A.; Schweizer, H.P.; Bearden, S.W.; Murphy, R.C.; Churchill, M.E.

J. Bacteriol.

188

784-788

665602

15634689

Altering substrate chain length specificity of an acylhomoserine lactone synthase in bacterial communication

2005

Brader, G.; Sjoblom, S.; Hyytiainen, H.; Sims-Huopaniemi, K.; Palva, E.T.

J. Biol. Chem.

280

10403-10409

720492

20624221

LuxR-type quorum-sensing regulators that are detached from common scents

2010

Tsai, C.S.; Winans, S.C.

Mol. Microbiol.

77

1072-1082

763418

29739899

Novel Xanthomonas campestris long-chain-specific 3-oxoacyl-acyl carrier protein reductase involved in diffusible signal factor synthesis

2018

Hu, Z.; Dong, H.; Ma, J.C.; Yu, Y.; Li, K.H.; Guo, Q.Q.; Zhang, C.; Zhang, W.B.; Cao, X.; Cronan, J.E.; Wang, H.

mBio

9

e00596-18

763477

31560825

A novel 3-oxoacyl-ACP reductase (FabG3) is involved in the xanthomonadin biosynthesis of Xanthomonas campestris pv. campestris

2019

Yu, Y.; Ma, J.; Guo, Q.; Ma, J.; Wang, H.

Mol. Plant Pathol.

20

1696-1709

Links to other databases for 3-oxooctanoyl-[acyl-carrier protein]

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Show Links (1 entry)