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BRENDA support

Ligand 2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine

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Basic Ligand Information

Molecular Structure
Picture of 2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H16N5O9P
2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine
VKMYTDDVUBGBDH-UUOKFMHZSA-N
Synonyms:
2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one, 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one, 2-amino-5-formylamino-6-(D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate
Pathway Source
Pathways


Show all pahtways known for Show all BRENDA pathways known for 2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-5-formylamino-6-(D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H2O = 2,5-diamino-6-(D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-5-formylamino-6-(D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H2O = 2,5-diamino-6-(D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1
-
pH 7.2, 70°C, apparent Km-value is about 1 mM at a concentration of 2 mM Fe2+, type of curve is typically indicative of homomeric cooperativity and suggests that ArfB may exhibit positive cooperative substrate binding

References & Links

Links to other databases for 2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine

ChEBI
PubChem
ChEBI
PubChem