Ligand p-hydroxyphenylacetaldoxime

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Basic Ligand Information

Molecular Structure
Picture of p-hydroxyphenylacetaldoxime (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H9NO2
p-hydroxyphenylacetaldoxime
TVXJJNJGTDWFLD-RMKNXTFCSA-N
Synonyms:
(1E)-(4-hydroxyphenyl)acetaldehyde oxime, (E)-4-Hydroxyphenylacetaldehyde-oxime, (E)-4-hydroxyphenylacetaldehyde oxime, (E)-4-hydroxyphenylacetaldoxime, (E)-p-hydroxyphenylacetaldehyde oxime, (E)-p-hydroxyphenylacetaldoxime, (E)-[4-hydroxyphenylacetaldehyde oxime], (E,Z)-4-hydroxyphenylacetaldehyde oxime, (Z)-4-Hydroxyphenylacetaldehyde-oxime, 4-hydroxyphenylacetaldehyde oxime, 4-hydroxyphenylacetaldoxime, 4-[(2E)-2-(hydroxyimino)ethyl]phenol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(E)-4-hydroxyphenylacetaldoxime + O2 + [reduced NADPH-hemoprotein reductase] = 1-aci-nitro-2-(4-hydroxyphenyl)-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(E)-4-hydroxyphenylacetaldoxime + O2 + [reduced NADPH-hemoprotein reductase] = 1-aci-nitro-2-(4-hydroxyphenyl)-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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(E)-4-hydroxyphenylacetaldoxime + O2 + [reduced NADPH-hemoprotein reductase] = 1-aci-nitro-2-(4-hydroxyphenyl)-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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4-hydroxyphenylacetaldoxime + [reduced NADPH-hemoprotein reductase] + O2 = hydroxy(4-hydroxyphenyl)acetonitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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(E,Z)-4-hydroxyphenylacetaldehyde oxime = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tyramine + NADPH + H+ + O2 = 4-[(2E)-2-(hydroxyimino)ethyl]phenol + NADP+ + H2O
show the reaction diagram
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L-tyrosine + 2 O2 + 2 [reduced NADPH-hemoprotein reductase] = (E)-[4-hydroxyphenylacetaldehyde oxime] + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
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tyrosine + 2 O2 + 2 [reduced NADPH-hemoprotein reductase] = (E)-4-hydroxyphenylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.62
-
pH 7.6, 30°C

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
-
-
0.007
-
pH 7.6, 30°C

References & Links

Links to other databases for p-hydroxyphenylacetaldoxime

ChEBI
PubChem
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PubChem