Ligand 3'-NADP+
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Basic Ligand Information
C21H28N7O17P3
3'-NADP+
HRJGRSFNJUHUBY-NNYOXOHSSA-O
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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ATP + NAD+ = ADP + 3'-NADP+
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Substrate in Enzyme-catalyzed Reactions (1 result)
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NADH + 3'-NADP+ = NAD+ + 3'-NADPH
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Product in Enzyme-catalyzed Reactions (4 results)
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2-oxopantoate + 3'-NADPH = (R)-pantoate + 3'-NADP+
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2,3-dihydrodipicolinate + 3'-NADPH + H+ = 2,3,4,5-tetrahydrodipicolinate + 3'-NADP+ + H2O
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ATP + NAD+ = ADP + 3'-NADP+
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GTP + NAD+ = GDP + 3'-NADP+
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Enzyme Cofactor/Cosubstrate (1 result)
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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noncompetitive with respect to NADPH
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Enzyme Kinetic Parameters
References & Links
Literature References (3)
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Steady-state kinetic mechanism of Escherichia coli UDP-N-acetylenolpyruvylglucosamine reductase
1995
Dhalla, A.M.; Yanchunas, J.Jr.; Ho, H.T.; Falk, P.J.; Villafranca, J.J.; Robertson, J.G.
Biochemistry
34
5390-5402
20beta-Hydroxysteroid dehydrogenase of neonatal pig testis: reverse catalytic (oxidation) reaction
1991
Ohno, S.; Nakajin, S.; Shinoda, M.
Chem. Pharm. Bull.
39
972-975
Comparative studies on nicotinamide nucleotide transhydrogenase from different sources
1974
Hoek, J.B.; Rydström, J.; Höjeberg, B.
Biochim. Biophys. Acta
333
237-245
Links to other databases for 3'-NADP+