Ligand Collagen

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Basic Ligand Information

Molecular Structure
Picture of Collagen (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C26H41N7O8R2
Collagen
CALVHBWWYCZXKE-UHFFFAOYSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (24 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
collagen + 2-oxoglutarate + O2 = 5-hydroxylysyl-collagen + succinate + CO2
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collagen + H2O + O2 = allysyl-collagen + NH3 + H2O2
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pro-collagen + H2O = collagen + collagen N-propeptide
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procollagen + H2O = collagen + collagen propeptide
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Substrate in Enzyme-catalyzed Reactions (59 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
collagen + 2-oxoglutarate + O2 = 4-hydroxyproline containing collagen + succinate + CO2
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collagen + 2-oxoglutarate + O2 = 5-hydroxylysyl-collagen + succinate + CO2
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collagen + H2O + O2 = ?
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UDP-alpha-D-glucose + collagen = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = Hydrolyzed collagen
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = Hydrolyzed collagen
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Collagen + H2O = ?
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Collagen + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pro-collagen + H2O = collagen + collagen N-propeptide
show the reaction diagram
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procollagen + H2O = collagen + collagen propeptide
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
250 kDa dimeric DDR1a entity is phosphorylated upon ligand stimulation
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adhesion of myeloid-macrophage cell lines to fibronectin is accompanied by marked stimulation of enzyme activity
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enhances MMP-2 activation by MT2-MMP
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibitor, noncompetitive with respect to all substrates of the reaction
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.000625
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0.000000548
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alpha-chain

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for Collagen

ChEBI
PubChem
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PubChem