Ligand monostearin

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Basic Ligand Information

Molecular Structure
Picture of monostearin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H42O4
monostearin
VBICKXHEKHSIBG-UHFFFAOYSA-N
Synonyms:
1-monostearin, 1-monostearoylglycerol, 1-stearoyl-rac-glycerol, 1-stearoyl-sn-glycerol, 1-stearoylglycerol, DL-alpha-stearin, glycerol stearate, monostearoylglycerol, sn-3-monostearoylglycerol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
palmitoyl-CoA + 1-monostearin = CoA + ?
show the reaction diagram
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oleoyl-CoA + sn-3-monostearoylglycerol = CoA + 1-oleoyl-3-stearoylglycerol
show the reaction diagram
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CDP-ethanolamine + 1-stearoylglycerol = CMP + ?
show the reaction diagram
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1-monostearin + H2O = stearic acid + glycerol
show the reaction diagram
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DL-alpha-stearin + H2O = ?
show the reaction diagram
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glycerol stearate + H2O = glycerol + stearate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerol + stearic acid = monostearin + H2O
show the reaction diagram
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distearin + H2O = monostearoylglycerol + stearate
show the reaction diagram
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1-stearoyl-lysophosphatidylcholine + H2O = 1-stearoyl-sn-glycerol + phosphorylcholine
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
approx. 10% stimulation at 0.8 mM, inhibition above
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2 mM, 58% inhibition
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slight stimulation below 0.8 mM, approx. 10% inhibition at 3.2 mM
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0.5 mM significantly reduce the P-glycoprotein protein expression, 0.1 mM of 1-monostearin does not have any significant effect on the expression of P-glycoprotein
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Enzyme Kinetic Parameters

References & Links

Links to other databases for monostearin

ChEBI
PubChem
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PubChem