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Ligand ethanolamine plasmalogen Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 3 H2 4 NO7 PR2
ethanolamine plasmalogen
1-alkenyl-2-acylglycerophosphoethanolamine, O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (3 results)
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O
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acyl-CoA + 1-alkenylglycerophosphoethanolamine = CoA + 1-alkenyl-2-acylglycerophosphoethanolamine
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Substrate in Enzyme-catalyzed Reactions (1 result)
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ethanolamine plasmalogen + H2O = lysoplasmalogen + fatty acid
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Product in Enzyme-catalyzed Reactions (4 results)
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + A + 2 H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O
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O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + reduced cytochrome b5 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized cytochrome b5 + 2 H2O
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acyl-CoA + 1-alkenylglycerophosphoethanolamine = CoA + 1-alkenyl-2-acylglycerophosphoethanolamine
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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inhibits hydrolysis of phosphatidylethanolamine
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links Literature References (7)
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Subcellular distribution and kinetic properties of rat brain phospholipases A1 and A2
1973
Woelk, H.; Porcellati, G.
Hoppe-Seyler's Z. Physiol. Chem.
354
90-100
Characterization of plasmalogen-selective phospholipase A2 from bovine brain
1996
Yang, H.C.; Farooqui, A.A.; Horrocks, L.A.
Adv. Exp. Med. Biol.
416
309-313
Enzymatic synthesis of plasmalogens. Characterization of the 1-O-alkyl-2-acyl-8n-glycero-3-phosphorylethanolamine desaturase from mucosa of hamster small intestine
1973
Paltauf, F.; Holasek, A.
J. Biol. Chem.
248
1609-1615
Evidence for a mixed function oxidase in the biosynthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine
1972
Wykle, R.L.; Blank, M.L.; Malone, B.; Snyder, F.
J. Biol. Chem.
247
5442-5447
Formation of ether lipids and wax esters in mammalian cells. Specificity of enzymes with regard to carbon chains of substrates
1982
Weber, N.; Richter, J.
Biochim. Biophys. Acta
711
197-207
On the substrate specificity of enol ether formation in rat brain. Metabolism of O-alkyl ethanediol phosphorylethanolamine
1975
Baumann, W.J.; Madson, T.H.; Chang, N.; Bandi, P.C.; Schmidt, H.H.O.
Biochem. Biophys. Res. Commun.
66
717-724
Acylation of 1-alkenylglycerophosphoethanolamine and 1-acylglycerophosphoethanolamine in guinea-pig heart microsomes
1987
Arthur, G.; Page, L.; Choy, P.C.
Biochim. Biophys. Acta
921
259-265
Links to other databases for ethanolamine plasmalogen