Ligand lupeol

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Basic Ligand Information

Molecular Structure
Picture of lupeol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H50O
lupeol
MQYXUWHLBZFQQO-QGTGJCAVSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2,3-oxidosqualene = lupeol
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2,3-oxidosqualene = lupeol
show the reaction diagram
-
-
(S)-2,3-oxidosqualene = lupeol
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
inhibition at 0.1 mM: oxidase 52%, reductase 38.4%
-
from Guioa villosa leaf extract
-
IC50: 0.048 mM, hACAT-1
-
a pentacyclic triterpene, isolated the ethanolic extract of Chuquiraga erinacea D. Don. subsp. erinacea leaves
-
isolated from Sorbus commixta stem bark, inhibits PTP1B in a selective and noncompetitive manner
-

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0034
-
pH 6.0, 37°C

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
2.24
-
-
0.048
-
IC50: 0.048 mM, hACAT-1
0.0056
-
pH 6.0, 37°C

References & Links

Links to other databases for lupeol

ChEBI
PubChem
ChEBI
PubChem