Ligand beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenyl

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Basic Ligand Information

Molecular Structure
Picture of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenyl (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H28N2O13
beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenyl
INMOOBMAIAWVBW-KDKNCOTBSA-N
Synonyms:
4-nitrophenyl-beta-lacto-N-bioside, 4-nitrophenyl-lacto-N-bioside, galactosyl-beta-1,3-N-acetyl-beta-D-glucosaminyl-p-nitrophenyl, galactosyl-beta-1,3-N-acetyl-D-glucosaminyl-beta-p-nitrophenyl, Galbeta(1,3)-GlcNAcbeta-4-nitrophenyl, Galbeta(1-3)GlcNAcbeta-O-p-nitrophenol, Galbeta1-3GlcNAcbeta-p-nitrophenol, p-nitrophenyl-Gal-(1,3)-beta-GlcNAc, p-Nitrophenyl-lacto-N-bioside

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenyl = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-p-nitrophenyl
show the reaction diagram
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GDP-beta-L-fucose + Galbeta(1-3)GlcNAcbeta-O-p-nitrophenol = GDP + Fucalpha(1-2)Galbeta(1-3)GlcNAcbeta-O-p-nitrophenol
show the reaction diagram
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CMP-N-acetylneuraminate + Galbeta(1,3)-GlcNAcbeta-4-nitrophenyl = ?
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
and other nitrophenyl-sugar-derivatives; strong inhibition under UV-radiation at 350 nm, specific for substrate binding site, preincubation with beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-benzyl partially protects
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.6
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AML cell line

References & Links

Links to other databases for beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-p-nitrophenyl

ChEBI
PubChem
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PubChem