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Ligand S-hexylglutathione
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Basic Ligand Information
hexyl-glutathione, hexyl-S-glutathione, hexylglutathione, hexyl glutathione, S-hexyl-glutathione, S-hexyl-GSH, S-hexyl glutathione
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open all tablesRoles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (3 results)
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EC NUMBER 
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-hexyl-glutathione + ascorbate + O2 = S-hexyl-gamma-Glu-Cys-NH2 + glyoxylate + dehydroascorbate + H2O
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Product in Enzyme-catalyzed Reactions (33 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
hexylcobalamin + [alkylcobalamin reductase] + glutathione = cob(I)alamin-[alkylcobalamin reductase] + S-hexylglutathione
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Inhibitor in Enzyme-catalyzed Reactions (373 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
0.01 mM, 21.7% inhibition of wild-type enzyme, 23% of mutant enzyme H144A, 10.8% of mutant enzyme V147A, 24.2% of mutant enzyme V147L, 14.7% of mutant enzyme R96A
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
binding structure with wild-type and mutant Y119E and F123A enzymes, overview
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
inhibitor binding does not induce significant conformational changes in the protein
slows degradation of the wild-type enzyme and mutant E161Q/E345Q in comparison with uncomplexed protein
3D Structure of Enzyme-Ligand-Complex (PDB) (289 results)
EC NUMBER
ENZYME 3D STRUCTURE
Enzyme Kinetic Parameters
KM Value (1 result)
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
Ki Value (3 results)
EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
IC50 Value (6 results)
EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00039
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IC50: 0.00031 mM for homodimeric enzyme, IC50: 0.00039 mM for heterodimeric enzyme
References & Links
Literature References (32)
Links to other databases for S-hexylglutathione
ChEBI
PubChem
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