Ligand L-methionine sulfone

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of L-methionine sulfone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H11NO4S
L-methionine sulfone
UCUNFLYVYCGDHP-BYPYZUCNSA-N
Synonyms:
(2S)-2-amino-4-(methylsulfonyl)butanoic acid, L-methionine sulphone, L-MetS, methionine sulfone

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-methionine sulfone + glyoxylate = 4-methylsulfonyl-2-oxobutanoate + glycine
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10 mM, 9.2% inhibition
-
poor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (83 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (7 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (5 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.005
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.033
-
pH 7.5, 22°C

References & Links

Links to other databases for L-methionine sulfone

ChEBI
PubChem
ChEBI
PubChem