Ligand L-aspartate beta-hydroxamate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of L-aspartate beta-hydroxamate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H8N2O4
L-aspartate beta-hydroxamate
ZBYVTTSIVDYQSO-REOHCLBHSA-N
Synonyms:
beta-aspartyl hydroxamate, beta-L-aspartohydroxamic acid, beta-L-aspartylhydroxamate, L-2-amino-4-(hydroxylamino)-4-oxobutanoic acid, L-aspartic acid-beta-hydroxamate, L-aspartic acid beta-hydroxamate, L-aspartyl-4-hydroxamate, L-aspartyl hydroxamate

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + L-aspartate beta-hydroxamate = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-Asn + hydroxylamine = L-2-amino-4-(hydroxylamino)-4-oxobutanoic acid + NH3
show the reaction diagram
-
-
ATP + L-Asp + hydroxylamine = AMP + diphosphate + Asn + beta-aspartyl hydroxamate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
48% inhibition at 5 mM
-
weak
-
a competitive and selective serine racemase inhibitor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
13
-
pH 8.0, 25°C, aspartokinase III

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.3
-
pH 8.0

References & Links

Links to other databases for L-aspartate beta-hydroxamate

ChEBI
PubChem
-
PubChem