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BRENDA support

Ligand 7alpha,27-dihydroxycholesterol

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Basic Ligand Information

Molecular Structure
Picture of 7alpha,27-dihydroxycholesterol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C27H46O3
7alpha,27-dihydroxycholesterol
RXMHNAKZMGJANZ-DTTSCKGMSA-N
Synonyms:
5-cholestene-3beta,7alpha,27 triol, 7-alpha,27-dihydroxycholesterol, cholest-5-ene-3beta,7alpha,27-triol
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
7alpha,27-dihydroxycholesterol + NAD+ = 7alpha,27-dihydroxy-4-cholesten-3-one + NADH
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O
show the reaction diagram
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.003
-
-

References & Links

Links to other databases for 7alpha,27-dihydroxycholesterol

ChEBI
PubChem
ChEBI
PubChem