Ligand 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate
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Basic Ligand Information
Molecular Structure

C8H9NO4
3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate
VJZTVPVXKYQRJZ-UHFFFAOYSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O2 + H3O+ = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+ + H2O
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Substrate in Enzyme-catalyzed Reactions (2 results)
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3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O2 + H3O+ = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+ + H2O
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3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP+ + H2O
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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The bacterial oxidation of vitamin B6. VII. Purification, properties, and mechanism of action of an oxygenase which cleaves the 3-hydroxypyridine ring
1969
Sparrow, L.G.; Ho, P.P.K.; Sundaram, T.K.; Zach, D.; Nyns, E.J.; Snell, E.E.
J. Biol. Chem.
244
2590-2600
Enzymes of vitamin B6 degradation. Purification and properties of 5-pyridoxic-acid oxygenase from Arthrobacter sp
1986
Nelson, M.J.K.; Snell, E.E.
J. Biol. Chem.
261
15115-15120
Links to other databases for 3-hydroxy-4-hydroxymethyl-2-methylpyridine-5-carboxylate