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succinic semialdehyde + NADPH + H+ = 4-hydroxybutyrate + NADP+
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succinic semialdehyde + NADH + H+ = 4-hydroxybutyrate + NAD+
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succinic semialdehyde + NADPH + H+ = 4-hydroxybutyrate + NADP+
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succinate semialdehyde + NAD(P)H + H+ = 4-hydroxybutanoate + NAD(P)+
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succinate semialdehyde + NADH + H+ = 4-hydroxybutanoate + NAD+
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succinate semialdehyde + NADPH + H+ = 4-hydroxybutanoate + NADP+
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succinic semialdehyde + NADH + H+ = 4-hydroxybutyrate + NAD+
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succinic semialdehyde + NADH + H+ = gamma-hydroxybutyrate + NAD+
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succinic semialdehyde + NADH + H+ = 4-hydroxybutyrate + NAD+
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succinic semialdehyde + NADPH + H+ = 4-hydroxybutyrate + NADP+
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succinate semialdehyde + NADH + H+ = 4-hydroxybutanoate + NAD+
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succinate semialdehyde + NADPH + H+ = 4-hydroxybutanoate + NADP+
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succinic semialdehyde + NADPH + H+ = 4-hydroxybutyrate + NADP+
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D-2-hydroxyglutarate + succinic semialdehyde = 2-oxoglutarate + 4-hydroxybutyrate
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L-3-hydroxybutyrate + succinic semialdehyde = acetoacetate + 4-hydroxybutyrate
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beta-alanine + pyruvate = 4-hydroxybutyrate + L-alanine
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gamma-butyrolactone + H2O = 4-hydroxy-butyric acid
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gamma-butyrolactone + H2O = 4-hydroxybutanoate
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gamma-butyrolactone + H2O = 4-hydroxybutanoic acid
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gamma-butyrolactone + H2O = 4-hydroxybutyric acid
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gamma-butyrolactone + H2O = gamma-hydroxybutyrate
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gamma-butyrolactone + H2O = 4-hydroxybutanoic acid
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Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of gamma-lactones. II. Metal ion effects, kinetics, and equilibria
1966
Fishbein, W.N.; Bessman, S.P.
J. Biol. Chem.
241
4842-4847
Kinetics of coupled gamma-hydroxybutyrate oxidation and D-glucuronate reduction by an NADP+-dependent oxidoreductase
1981
Kaufman, E.E.; Nelson, T.
J. Biol. Chem.
256
6890-6894
An overview of gamma-hydroxybutyrate catabolism: the role of the cytosolic NADP+-dependent oxidoreductase EC 1.1.1.19 and of a mitochondrial hydroxyacid-oxoacid transhydrogenase in the initial, rate-limiting step in this pathway
1991
Kaufman, E.E.; Nelson, T.
Neurochem. Res.
16
965-974
Purification and properties of an NADPH-linked aldehyde reductase from rat kidney
1983
Takahashi, N.; Saito, T.; Tomita, K.
Biochim. Biophys. Acta
748
444-452
Purification and properties of NADP-linked, alcohol dehydrogenase from Entamoeba histolytica
1982
Lo, H.S.; Chang, C.J.
J. Parasitol.
68
372-377
Purification and characterization of an NAD-malic enzyme from Bradyrhizobium japonicum A1017
1998
Chen, F.; Okabe, Y.; Osano, K.; Tajima, S.
Appl. Environ. Microbiol.
64
4073-4075
Enzymatic utilization of gamma-hydroxybutyric acid
1960
Nirenberg, M.W.; Jakoby, W.B.
J. Biol. Chem.
235
954-960
Purification and characterization of the oxygen-sensitive 4-hydroxybutanoate dehydrogenase from Clostridium kluyveri
1995
Wolff, R.A.; Kenealy W.R.
Protein Expr. Purif.
6
206-212
Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria
1988
Kaufman, E.E.; Nelson, T.; Fales, H.M.; Levin, D.M.
J. Biol. Chem.
263
16872-16879
Inhibition of p-hydroxybenzoate hydroxylase by anions: possible existence of two anion-binding sites in the site for reduced nicotinamide adenine dinucleotide phosphate
1983
Shoun, H.; Arima, K.; Beppu, T.
J. Biochem.
93
169-176
Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase
2000
Born, T.L.; Franklin, M.; Blanchard, J.S.
Biochemistry
39
8556-8564
Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium
1978
Barker, H.A.; Jemg, I.M.; Neff, N.; Robertson, J.M.; Tam, F.K.; Hosaka, S.
J. Biol. Chem.
253
1219-1225
Reliable, sensitive, rapid and quantitative enzyme-based assay for gamma-hydroxybutyric acid (GHB)
2004
Bravo, D.T.; Harris, D.O.; Parsons, S.M.
J. Forensic Sci.
49
379-387
Inhibition of the Class II HMG-CoA reductase of Pseudomonas mevalonii
2004
Hedl, M.; Rodwell, V.W.
Protein Sci.
13
1693-1697
Identification of the gene encoding hydroxyacid-oxoacid transhydrogenase, an enzyme that metabolizes 4-hydroxybutyrate
2006
Kardon, T.; Noel, G.; Vertommen, D.; Van Schaftingen, E.
FEBS Lett.
580
2347-2350
-
Characterization of two D-b-hydroxybutyrate dehydrogenase populations in heavy and light mitochondria from jerboa (Jaculus orientalis) liver
2006
Mountassif, D.; Kabine, M.; Latruffe, N.; El Kebbaj, M.S.
Comp. Biochem. Physiol. B
143B
285-293
Kinetic mechanism of a recombinant Arabidopsis glyoxylate reductase: studies of initial velocity, dead-end inhibition and product inhibition
2007
Hoover, G.J.; Prentice, G.A.; Merrill, A.R.; Shelp, B.J.
Can. J. Bot.
85
896-902
Enzymes involved in the metabolism of gamma-hydroxybutyrate in SH-SY5Y cells: identification of an iron-dependent alcohol dehydrogenase ADHFe1
2009
Lyon, R.C.; Johnston, S.M.; Panopoulos, A.; Alzeer, S.; McGarvie, G.; Ellis, E.M.
Chem. Biol. Interact.
178
283-287
Metabolite profiling reveals YihU as a novel hydroxybutyrate dehydrogenase for alternative succinic semialdehyde metabolism in Escherichia coli
2009
Saito, N.; Robert, M.; Kochi, H.; Matsuo, G.; Kakazu, Y.; Soga, T.; Tomita, M.
J. Biol. Chem.
284
16442-16451
A propionate CoA-transferase of Ralstonia eutropha H16 with broad substrate specificity catalyzing the CoA thioester formation of various carboxylic acids
2012
Lindenkamp, N.; Schuermann, M.; Steinbuechel, A.
Appl. Microbiol. Biotechnol.
97
7699-7709
Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea
2013
Hawkins, A.S.; Han, Y.; Bennett, R.K.; Adams, M.W.; Kelly, R.M.
J. Biol. Chem.
288
4012-4022
Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
2014
Hawkins, A.B.; Adams, M.W.; Kelly, R.M.
Appl. Environ. Microbiol.
80
2536-2545
Identification of missing genes and enzymes for autotrophic carbon fixation in crenarchaeota
2011
Ramos-Vera, W.H.; Weiss, M.; Strittmatter, E.; Kockelkorn, D.; Fuchs, G.
J. Bacteriol.
193
1201-1211
Characterization of propionate CoA-transferase from Ralstonia eutropha H16
2014
Volodina, E.; Schuermann, M.; Lindenkamp, N.; Steinbuechel, A.
Appl. Microbiol. Biotechnol.
98
3579-3589
Ammonia-oxidizing archaea use the most energy-efficient aerobic pathway for CO2 fixation
2014
Koenneke, M.; Schubert, D.; Brown, P.; Huegler, M.; Standfest, S.; Schwander, T.; Schada Von Borzyskowski, L.; Erb, T.; Stahl, D.; Berg, I.
Proc. Natl. Acad. Sci. USA
111
8239-8244
Kinetics aspects of Gamma-hydroxybutyrate dehydrogenase
2020
Taxon, E.S.; Halbers, L.P.; Parsons, S.M.
Biochim. Biophys. Acta Proteins Proteom.
1868
140376
Engineering and characterization of hybrid carboxylic acid reductases
2019
Kramer, L.; Le, X.; Hankore, E.D.; Wilson, M.A.; Guo, J.; Niu, W.
J. Biotechnol.
304
52-56