Ligand 3-bromo-L-tyrosine
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information
Molecular Structure
C9H10BrNO3
3-bromo-L-tyrosine
HGWOSUKIFQMEIF-ZETCQYMHSA-N
3-bromo-L-Tyr, monobromotyrosine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-bromo-L-tyrosine + NADP+ + bromide = 3,5-dibromo-L-tyrosine + NADPH + H+
-
3-bromo-L-tyrosine + NADPH + H+ = L-tyrosine + NADP+ + Br-
-
3-bromo-L-Tyr + H2O = 3-bromophenol + pyruvate + NH3
-
3-bromo-L-tyrosine + H2O = 3-bromophenol + pyruvate + NH3
-
Product in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
tyrosine + Br- + H2O2 = monobromotyrosine + dibromotyrosine
-
3-bromophenol + pyruvate + NH3 = 3-bromo-L-Tyr + H2O
-
3D Structure of Enzyme-Ligand-Complex (PDB) (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.069
-
at pH 7.4, temperature not specified in the publication
KM Value (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.008
-
at pH 7.4, temperature not specified in the publication
References & Links
Literature References (6)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Syntheses of L-tyrosine-related amino acids by tyrosine phenol-lyase of Citrobacter intermedius
1981
Nagasawa, T.; Utagawa, T.; Goto, J.; Kim, C.J.; Tani Y.; Kumagai, H.; Yamada, H.
Eur. J. Biochem.
117
33-40
Chloroperoxidase. II. Utilization of halogen anions
1966
Hager, L.P.; Morris, D.R.; Brown, F.S.; Eberwein, H.
J. Biol. Chem.
241
1769-1777
Aminoacrylate intermediates in the reaction of Citrobacter freundii tyrosine phenol-lyase
2006
Phillips, R.S.; Chen, H.Y.; Faleev, N.G.
Biochemistry
45
9575-9583
A mammalian reductive deiodinase has broad power to dehalogenate chlorinated and brominated substrates
2009
McTamney, P.M.; Rokita, S.E.
J. Am. Chem. Soc.
131
14212-14213
The distribution and mechanism of iodotyrosine deiodinase defied expectations
2017
Sun, Z.; Su, Q.; Rokita, S.E.
Arch. Biochem. Biophys.
632
77-87
Functional analysis of iodotyrosine deiodinase from Drosophila melanogaster
2016
Phatarphekar, A.; Rokita, S.E.
Protein Sci.
25
2187-2195
Links to other databases for 3-bromo-L-tyrosine
close all tables 
open all tables
top
