Ligand 3-(4-hydroxyphenyl)lactate

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Basic Ligand Information

Molecular Structure
Picture of 3-(4-hydroxyphenyl)lactate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H10O4
3-(4-hydroxyphenyl)lactate
JVGVDSSUAVXRDY-UHFFFAOYSA-N
Synonyms:
2-hydroxy-3-(4-hydroxyphenyl)propanoate, 4-hydroxyphenyl-DL-lactic acid, 4-hydroxyphenyllactate, DL-4-hydroxyphenyllactate, DL-p-hydroxy-beta-phenyllactate, p-Hydroxy-3-phenyllactate, p-hydroxyphenyllactate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-(4-hydroxyphenyl)lactate + NAD+ = 4-hydroxyphenylpyruvate + NADH
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
p-hydroxyphenyllactate + NAD+ = p-hydroxyphenylpyruvate + NADH
show the reaction diagram
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3-(4-hydroxyphenyl)lactate + NAD+ = 4-hydroxyphenylpyruvate + NADH
show the reaction diagram
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DL-p-hydroxy-beta-phenyllactate + 2,6-dichlorophenolindophenol = (4-hydroxyphenyl)pyruvate + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-(4-hydroxyphenyl)-2-oxopropanoate + NADH + H+ = 2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD+
show the reaction diagram
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p-hydroxyphenylpyruvate + NADH + H+ = 2-hydroxy-3-(4-hydroxyphenyl)propanoate
show the reaction diagram
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4-hydroxyphenylpyruvate + NADH = 4-hydroxyphenyllactate + NAD+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition above 10 mM, competitive
-
weak
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weak
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Enzyme Kinetic Parameters

KM Value (15 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 3-(4-hydroxyphenyl)lactate

ChEBI
PubChem
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PubChem