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Development of a fluorescence-based enzyme assay of human 5-lipoxygenase
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Indole derivatives as potent inhibitors of 5-lipoxygenase: design, synthesis, biological evaluation, and molecular modeling
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Involvement of 5-lipoxygenase in survival of Epstein-Barr virus (EBV)-converted B lymphoma cells
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5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
2008
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Investigations concerning the COX/5-LOX inhibiting and hydroxyl radical scavenging potencies of novel 4,5-diaryl isoselenazoles
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Role of 5-lipoxygenase in myocardial ischemia-reperfusion injury in mice
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Regulatory effects of arachidonate 5-lipoxygenase on hepatic MTP activity and VLDL-TG and ApoB secretion in obese mice
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Identification of natural-product-derived inhibitors of 5-lipoxygenase activity by ligand-based virtual screening
2007
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5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid
2008
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5-LOX, 12-LOX and 15-LOX in immature forms of human leukemic blasts
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The 5-lipoxygenase enzymatic pathway in the mouse brain: Young versus old
2007
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Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors
2008
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Prostaglandins Leukot. Essent. Fatty Acids
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5-Lipoxygenase/cyclooxygenase-2 cross-talk through cysteinyl leukotriene receptor 2 in endothelial cells
2007
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Development of a method for expression and purification of the regulatory C2-like domain of human 5-lipoxygenase
2008
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5-Lipoxygenase: regulation of expression and enzyme activity
2007
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The structure and peroxidase activity of a 33kD catalase-related protein from Mycobacterium avium ssp. paratuberculosis
2009
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Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis
2010
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Biochem. Biophys. Res. Commun.
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Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: Role of tryptophan 102
2010
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5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity
2010
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Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth
2010
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Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer
2010
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5-Lipoxygenase is a key determinant of acute myocardial inflammation and mortality during Trypanosoma cruzi infection
2010
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Microbes Infect.
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Identification of 4-[4-(4-fluoro-phenyl)-thiazol-2-ylamino]-2,6-dimethyl-phenol (KR-33749) as an inhibitor of 5-lipoxygenase with potent antiinflammatory activity
2010
Cho, Y.S.; Kim, C.H.; Surh, J.H.; Kang, N.S.; Yoo, S.E.; Cheon, H.G.
Pharmacology
86
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Acrolein increases 5-lipoxygenase expression in murine macrophages through activation of ERK pathway
2010
Kim, C.E.; Lee, S.J.; Seo, K.W.; Park, H.M.; Yun, J.W.; Bae, J.U.; Bae, S.S.; Kim, C.D.
Toxicol. Appl. Pharmacol.
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Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin
2006
Yu, Z.; Schneider, C.; Boeglin, W.E.; Brash, A.R.
Arch. Biochem. Biophys.
455
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ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid
2014
Smyrniotis, C.J.; Barbour, S.R.; Xia, Z.; Hixon, M.S.; Holman, T.R.
Biochemistry
53
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Molecular cloning and functional characterization of arachidonate 5-lipoxygenase (Alox5), and its expression in response to the ratio of linolenic acid to linoleic acid in diets of large yellow croaker (Larmichthys crocea)
2016
Wang, T.; Zuo, R.; Mai, K.; Xu, W.; Ai, Q.
Comp. Biochem. Physiol. B
201
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Further studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenase
2014
Peduto, A.; Bruno, F.; Dehm, F.; Krauth, V.; de Caprariis, P.; Weinigel, C.; Barz, D.; Massa, A.; De Rosa, M.; Werz, O.; Filosa, R.
Eur. J. Med. Chem.
81
492-498
Show all BRENDA pathways known for (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
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