Ligand streptamine
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Basic Ligand Information
Molecular Structure
C6H14N2O4
streptamine
ANLMVXSIPASBFL-FAEUDGQSSA-N
1,3-diamino-1,3-dideoxy-scyllo-inositol
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (5 results)
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streptamine + 2-oxoglutaramate = amino-scyllo-inositol + L-glutamine
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streptamine + keto-scyllo-inositol = amino-scyllo-inositol + amino-deoxy-keto-scyllo-inositol
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1,3-diamino-1,3-dideoxy-scyllo-inositol + dihydrostreptomycin 6-phosphate = ?
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1,3-diamino-1,3-dideoxy-scyllo-inositol + p-nitrophenyl phosphate = ?
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Enzyme Kinetic Parameters
References & Links
Literature References (4)
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Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine
1973
Walker, J.B.; Skorvaga, M.
J. Biol. Chem.
248
2441-2446
Enzymatic synthesis of streptidine from scyllo-inosamine
1967
Walker, J.B.; Walker, M.S.
Biochemistry
6
3821-3829
ATP:inosamine phosphotransferase(s)
1975
Walker, J.B.
Methods Enzymol.
43
444-451
Reactions catalyzed by purified L-glutamine:keto-scyllo-inositol aminotransferase, an enzyme required for biosynthesis of aminocyclitol antibiotics
1989
Lucher, L.A.; Chen, Y.M.; Walker, J.B.
Antimicrob. Agents Chemother.
33
452-459
Links to other databases for streptamine
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