print visible entries

print all entries

Ligand SUMO

Basic Ligand Information

close all tables

open all tables

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (18 results)

top print hide

Show Natural Product (18 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.4.22.B67

polySUMO-protein conjugate + H2O = SUMO + SUMO-SUMO + SUMO-SUMO-SUMO + truncated polySUMO-protein conjugate

-

-

3.4.22.B67

polySUMO-protein conjugate + H2O = SUMO + truncated polySUMO-protein conjugate + H2O

-

-

3.4.22.B70

SUMO-Elk-1 conjugate + H2O = SUMO + Elk-1

-

-

3.4.22.B70

SUMO-GATA 1 conjugate + H2O = SUMO + GATA1

-

-

3.4.22.B70

SUMO-hypoxia-inducible factor 1 conjugate + H2O = SUMO + hypoxia-inducible factor 1

-

-

3.4.22.B70

SUMO-STAT3 protein conjugate + H2O = SUMO + STAT3 protein

-

-

3.4.22.B71

(SUMO-1)-Mdm2 conjugate + H2O = SUMO + Mdm2

-

-

3.4.22.B71

SUMO-C/EBPbeta + H2O = SUMO + C/EBPbeta

-

-

3.4.22.B71

SUMO-Mdm2 conjugate + H2O = SUMO + Mdm2

-

-

3.4.22.B71

SUMO-Pc2/CBX4 conjugate + H2O = SUMO + Pc2/CBX4

-

-

3.4.22.B71

SUMOylated myocyte-specific enhancer factor-2A + H2O = deSUMOylated myocyte-specific enhancer factor-2A + SUMO

-

-

3.4.22.B72

SUMOylated FOXC2 + H2O = FOXC2 + SUMO

-

-

3.4.22.B72

SUMOylated GTPase Drp1 + H2O = GTPase Drp1 + SUMO

-

-

3.4.22.B72

SUMOylated RbBP5 + H2O = RbBP5 + SUMO

-

-

3.4.22.B67

2 entries

3.4.22.B70

4 entries

3.4.22.B71

5 entries

3.4.22.B72

3 entries

3.4.22.B73

SUMOylated dynamin related protein + H2O = dynamin related protein + SUMO

-

-

3.4.22.B74

SUMO-modified promyelocytic leukemia protein + H2O = SUMO + promyelocytic leukemia protein

-

-

3.4.22.B75

SUMOylated c-Myc + H2O = deSUMOylated c-Myc + SUMO

-

-

3.4.22.B75

SUMOylated HP1alpha + H2O = HP1alpha + SUMO

-

-

3.4.22.B75

2 entries

Product in Enzyme-catalyzed Reactions (26 results)

top print hide

Show Product (26 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.4.22.68

SUMO-GFP fusion substrate + H2O = SUMO + GFP

-

-

3.4.22.B67

hexa-SUMO + H2O = SUMO + ?

-

-

3.4.22.B67

polySUMO-protein conjugate + H2O = SUMO + SUMO-SUMO + SUMO-SUMO-SUMO + truncated polySUMO-protein conjugate

-

-

3.4.22.B67

polySUMO-protein conjugate + H2O = SUMO + truncated polySUMO-protein conjugate + H2O

-

-

3.4.22.B67

SUMO-modified-Bir1 kinetochore protein + H2O = SUMO + Bir1 kinetochore protein

-

-

3.4.22.B67

SUMO-modified-Cep3 kinetochore protein + H2O = SUMO + Cep3 kinetochore protein

-

-

3.4.22.B67

SUMO-modified-Ndc10 kinetochore protein + H2O = SUMO + Ndc10 kinetochore protein

-

-

3.4.22.B67

tetra-SUMO + H2O = SUMO + ?

-

-

3.4.22.B70

SUMO-7-amido-4-methylcoumarin + H2O = SuMo + 7-amino-4-methylcoumarin

-

-

3.4.22.B70

SUMO-Elk-1 conjugate + H2O = SUMO + Elk-1

-

-

3.4.22.B70

SUMO-GATA 1 conjugate + H2O = SUMO + GATA1

-

-

3.4.22.B70

SUMO-homeodomain-interacting protein kinase 1 conjugate + H2O = SUMO + homeodomain-interacting protein kinase 1 conjugate

-

-

3.4.22.B70

SUMO-hypoxia-inducible factor 1 conjugate + H2O = SUMO + hypoxia-inducible factor 1

-

-

3.4.22.B70

SUMO-STAT3 protein conjugate + H2O = SUMO + STAT3 protein

-

-

3.4.22.B71

(SUMO-1)-Mdm2 conjugate + H2O = SUMO + Mdm2

-

-

3.4.22.B71

SUMO-C/EBPbeta + H2O = SUMO + C/EBPbeta

-

-

3.4.22.B71

SUMO-Mdm2 conjugate + H2O = SUMO + Mdm2

-

-

3.4.22.B71

SUMO-Pc2/CBX4 conjugate + H2O = SUMO + Pc2/CBX4

-

-

3.4.22.B71

SUMOylated myocyte-specific enhancer factor-2A + H2O = deSUMOylated myocyte-specific enhancer factor-2A + SUMO

-

-

3.4.22.B72

SUMOylated FOXC2 + H2O = FOXC2 + SUMO

-

-

3.4.22.B72

SUMOylated GTPase Drp1 + H2O = GTPase Drp1 + SUMO

-

-

3.4.22.B72

SUMOylated RbBP5 + H2O = RbBP5 + SUMO

-

-

3.4.22.B67

7 entries

3.4.22.B70

6 entries

3.4.22.B71

5 entries

3.4.22.B72

3 entries

3.4.22.B73

SUMOylated dynamin related protein + H2O = dynamin related protein + SUMO

-

-

3.4.22.B74

SUMO-modified promyelocytic leukemia protein + H2O = SUMO + promyelocytic leukemia protein

-

-

3.4.22.B75

SUMOylated c-Myc + H2O = deSUMOylated c-Myc + SUMO

-

-

3.4.22.B75

SUMOylated HP1alpha + H2O = HP1alpha + SUMO

-

-

3.4.22.B75

2 entries

Activator in Enzyme-catalyzed Reactions (1 result)

top print hide

Show Activating Compound (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.4.22.B71

SUMO domain enhances catalysis of SENP2, substrate induced activation

715489

-

Enzyme Kinetic Parameters

References & Links

Literature References (1)

top print hide

Show Reference (1 entry)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

715489

17591783

Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs

2007

Mikolajczyk, J.; Drag, M.; Bekes, M.; Cao, J.T.; Ronai, Z.; Salvesen, G.S.

J. Biol. Chem.

282

26217-26224

Links to other databases for SUMO

top print hide

Show Links (1 entry)