Ligand O-demethylpuromycin
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Basic Ligand Information
Molecular Structure

C21H27N7O5
O-demethylpuromycin
NVZJDPXVSWFFJJ-YXDKPKCJSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin
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Substrate in Enzyme-catalyzed Reactions (1 result)
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S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links
Literature References (5)
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Biosynthesis of puromycin in Streptomyces alboniger. Enzymatic methylation of O-demethylpuromycin
1969
Rao, M.M.; Rebello, P.F.; Pogell, B.M.
J. Biol. Chem.
244
112-118
S-Adenosylmethionine: O-demethylpuromycin O-methyltransferase
1975
Pogell, B.M.
Methods Enzymol.
43
508-515
Biosynthesis of puromycin in Streptomyces alboniger: regulation and properties of O-demethylpuromycin O-methyltransferase
1975
Sankaran, L.; Pogell, B.M.
Antimicrob. Agents Chemother.
8
721-732
Biosynthesis of puromycin by Streptomyces alboniger: Characterization of puromycin N-acetyltransferase
1985
Vara, J.; Perez-Gonzalez, J.A.; Jimenez, A.
Biochemistry
24
8074-8081
Molecular analysis of the dmpM gene encoding an O-demethyl puromycin O-methyltransferase from Streptomyces alboniger
1991
Lacalle, R.A.; Ruiz, D.; Jimenez, A
Gene
109
55-61
Links to other databases for O-demethylpuromycin