We're sorry, but BRENDA doesn't work properly without JavaScript. Please make sure you have JavaScript enabled in your browser settings.
Ligand IDPmannose Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C1 6 H2 4 N4 O1 6 P2
IDPmannose
MDCWIRPAAZMRRI-RYRBFGMPSA-N
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
IDPmannose + diphosphate = ITP + D-mannose 1-phosphate
-
Substrate in Enzyme-catalyzed Reactions (2 results)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
IDPmannose + diphosphate = ITP + mannose 1-phosphate
-
IDPmannose + diphosphate = ITP + D-mannose 1-phosphate
-
Product in Enzyme-catalyzed Reactions (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ITP + alpha-D-mannose 1-phosphate = IDPmannose + diphosphate
-
Enzyme Kinetic Parameters
KM Value (1 result)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
References & Links Literature References (7)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Sugar nucleotide reactions in Arthrobacter. I. Guanosine diphosphate mannose pyrophosphorylase: purification and properties
1964
Preiss, J.; Wood, E.
J. Biol. Chem.
239
3119-3126
GDP-mannose pyrophosphorylase. Purification to homogeneity, properties, and utilization to prepare photoaffinity analogs
1993
Szumilo, T.; Drake, R.R.; York, J.L.; Elbein, A.D.
J. Biol. Chem.
268
17943-17950
Purification of GTP:alpha-D-mannose-1-phosphate guanyltransferase
1985
Smoot, J.W.; Serif, G.S.
Eur. J. Biochem.
148
83-87
Purification and properties of mycobacterial GDP-mannose pyrophosphorylase
1999
Ning, B.; Elbein, A.D.
Arch. Biochem. Biophys.
362
339-345
Cloning, expression and characterization of the pig liver GDP-mannose pyrophosphorylase: evidence that GDP-mannose and GDP-Glc pyrophosphorylases are different proteins
2000
Ning, B.; Elbein, A.D.
Eur. J. Biochem.
267
6866-6874
Purification and properties of guanosine diphosphate hexose pyrophosphorylase from mammalian tissues
1966
Verachtert, H.; Rodriguez, P.; Bass, S.T.; Hansen, R.G.
J. Biol. Chem.
241
2007-2013
-
GDP-hexose pyrophosphorylase from liver
1966
Hansen, R.G.; Verachtert, H.; Rodriguez, P.; Bass, S.T.
Methods Enzymol.
8
269-271
Links to other databases for IDPmannose