Ligand homocystine
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Basic Ligand Information
C8H16N2O4S2
homocystine
ZTVZLYBCZNMWCF-UHFFFAOYSA-N
Related pathways
Roles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)
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GSH + homocystine = GSSG + homocysteine
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Substrate in Enzyme-catalyzed Reactions (5 results)
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2 glutathione + homocystine = glutathione disulfide + 2 homocysteine
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2 lysine + homocystine = glutathione disulfide + 2 homocysteine
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cysteine + homocystine = cystine + 2 homocysteine
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GSH + homocystine = GSSG + homocysteine
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
References & Links
Literature References (5)
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A thiol-disulfide transhydrogenase from yeast
1968
Nagai, S.; Black, S.
J. Biol. Chem.
243
1942-1947
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Thiol-disulfide transhydrogenase from baker's yeast and a new method for the direct assay of an enzyme-catalyzed thiol-disulfide interchange activity
1973
Minoda, Y.; Kurane, R.; Yamada, K.
Agric. Biol. Chem.
37
2511-2516
Glutathione-homocystine transhydrogenase
1955
Racker, E.
J. Biol. Chem.
217
867-874
Purification and some properties of rat liver cysteine oxidase (cysteine dioxygenase)
1976
Sakakibara, S.; Yamaguchi, K.; Hosokawa, Y.; Kohashi, N.; Ueda, I.; Sakamoto, Y.
Biochim. Biophys. Acta
422
273-279
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Characterization of glutathione-homocystine transhydrogenase as a novel isoform of glutathione S-transferase from Aspergillus flavipes
2015
El-Sayed, A.; Hassan, A.; Yassin, M.; Hassan, A.
Pharm. Chem. J.
49
373-383
Links to other databases for homocystine
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