Ligand 12-hydroxylauric acid

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Basic Ligand Information

Molecular Structure
Picture of 12-hydroxylauric acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H24O3
12-hydroxylauric acid
ZDHCZVWCTKTBRY-UHFFFAOYSA-N
Synonyms:
12-hydroxy-dodecanoic acid, 12-hydroxydodecanoate, 12-Hydroxydodecanoic acid, 12-hydroxydodedecanoic acid, omega-hydroxylauric acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
12-hydroxydodecanoic acid + glutathione + NAD+ = S-(11-carboxy)undecanyl-glutathione + NADH + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
12-hydroxydodecanoate + NAD+ = 12-oxododecanoic acid + NADH
show the reaction diagram
12-hydroxydodecanoic acid + NAD+ + H2O = ? + NADH
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12-hydroxydodecanoic acid + NADH = ? + NAD+
show the reaction diagram
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12-hydroxydodecanoic acid + O2 = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lauric acid + H2O2 = omega-1-hydroxylauric acid + omega-2-hydroxylauric acid + omega-hydroxylauric acid + H2O
show the reaction diagram
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lauric acid + [reduced NADPH-hemoprotein reductase] + O2 = 12-hydroxydodecanoic acid + [oxidized NADPH-hemoprotein reductase] + H2O
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12-hydroxylauric acid + reduced NADPH-hemoprotein reductase + O2 = 12-hydroxy-dodecanoic acid + oxidized NADPH-hemoprotein reductase + H2O
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (14 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (19 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.7
-
-
1.7
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References & Links

Links to other databases for 12-hydroxylauric acid

ChEBI
PubChem
ChEBI
PubChem