Ligand geranylgeraniol

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Basic Ligand Information

Molecular Structure
Picture of geranylgeraniol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H34O
geranylgeraniol
OJISWRZIEWCUBN-QIRCYJPOSA-N
Synonyms:
(2E,6E)-geranylgeraniol, (E,E,E)-geranylgeraniol, geranyl geraniol

Show all pahtways known for Show all BRENDA pathways known for geranylgeraniol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geranylgeraniol + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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geranylgeraniol + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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ATP + geranylgeraniol = ADP + geranylgeranyl phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geranylgeranyl diphosphate + H2O = geranylgeraniol + diphosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geranylgeraniol + NADP+ = geranylgeranial + NADPH + H+
show the reaction diagram
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geranylgeraniol + NAD+ = ? + NADH + H+
show the reaction diagram
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geranylgeraniol + NAD+ = geranylgeranial + NADH + H+
show the reaction diagram
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geranylgeraniol + [reduced NADPH-hemoprotein reductase] + O2 = 18-hydroxygeranylgeraniol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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geranylgeraniol + reduced ferredoxin = 14,15-dihydrogeranylgeraniol + oxidized ferredoxin
show the reaction diagram
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acetyl-CoA + geranylgeraniol = CoA + ?
show the reaction diagram
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ATP + (2E,6E)-geranylgeraniol = ADP + (2E,6E)-geranylgeranyl phosphate
show the reaction diagram
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ATP + (E,E,E)-geranylgeraniol = ADP + (E,E,E)-geranylgeraniyl phosphate
show the reaction diagram
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geranylgeraniol + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
geranylgeranial + NADPH + H+ = geranylgeraniol + NADP+
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
presence of peptide NRLLLTG eliminates stimulatory effect
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.008
-
pH 7.4, 25°C, recombinant enzyme

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.001
-
pH 7.4, 25°C, recombinant enzyme
0.032
-
at pH 7.4 and 25°C
0.000027
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pH 7.0, 55°C, assay with membrane fraction

References & Links

Links to other databases for geranylgeraniol

ChEBI
PubChem
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PubChem