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BRENDA support

Ligand N-acetyl-L-alanine

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Basic Ligand Information

Molecular Structure
Picture of N-acetyl-L-alanine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H9NO3
N-acetyl-L-alanine
KTHDTJVBEPMMGL-VKHMYHEASA-N
Synonyms:
Ac-A, Ac-Ala, acetyl-Ala, acetyl-L-Ala, N-acetyl-Ala, N-acetyl-L-Ala, N-acetylalanine, N-alpha-acetyl-L-alanine, Nalpha-acetyl-L-alanine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetyl-L-alanine + H2O = acetate + L-alanine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-acetylalanine + H2O = acetate + alanine
show the reaction diagram
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Nalpha-acetyl-L-alanine + H2O = L-alanine + acetate
show the reaction diagram
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N-acetylalanine + H2O = acetate + alanine
show the reaction diagram
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N-acetyl-L-alanine + H2O = ?
show the reaction diagram
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N-acetyl-L-alanine + H2O = L-alanine + acetate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (68 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-alanine = CoA + N-acetyl-L-alanine
show the reaction diagram
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N-acetyl-L-Ala-1-naphthyl ester + H2O = N-acetyl-L-Ala + 1-naphthol
show the reaction diagram
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N-acetyl-Ala-Ala-Ala + H2O = N-acetyl-L-alanine + Ala-Ala
show the reaction diagram
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N-acetyl-Ala-Ala-Ala + H2O = N-acetyl-Ala + Ala-Ala
show the reaction diagram
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Acetyl-Ala-Ala-Ala + H2O = Acetyl-Ala + Ala-Ala
show the reaction diagram
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Acetyl-Ala methyl ester + H2O = Acetyl-Ala + methanol
show the reaction diagram
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acetyl-L-Ala methyl ester + H2O = acetyl-L-Ala + methanol
show the reaction diagram
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Ac-AGPRPTRIAFGA-NH2 + H2O = N-acetyl-L-alanine + GPRPTRIAFGA-NH2
show the reaction diagram
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acetyl-Ala-4-nitroanilide + H2O = acetyl-Ala + 4-nitroaniline
show the reaction diagram
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N-acetyl-Ala-Ala-Ala-Ala = N-acetyl-Ala + Ala-Ala-Ala
show the reaction diagram
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Acetyl-Ala-Ala-Ala-Ala + H2O = Ala-Ala-Ala + acetyl-Ala
show the reaction diagram
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N-acetyl-D-alanine = N-acetyl-L-alanine
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (911 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.89
-
pH 8.0, 30°C
27.86
-
pH 7.5, 65°C, preincubation with CoCl2

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5.45
-
pH 7.5, 37°C, purified recombinant wild-type enzyme
2.96
-
pH 8.0, 30°C
36.12
-
pH 7.5, 65°C, preincubation with CoCl2
41
-
-

References & Links

Links to other databases for N-acetyl-L-alanine

ChEBI
PubChem
ChEBI
PubChem