Ligand 5-L-glutamyl-L-valine
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Basic Ligand Information
Molecular Structure
C10H18N2O5
5-L-glutamyl-L-valine
AQAKHZVPOOGUCK-XPUUQOCRSA-N
5-L-glutamyl-L-Val, 5-L-glutamyl-Val, gamma-glutamylvaline, gamma-L-Glu-L-Val, gamma-L-Glu-L-valine, L-gamma-glutamyl-L-valine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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5-L-glutamyl-L-Val + Gly-Gly = L-Val + 5-L-glutamyl-Gly-Gly
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5-L-glutamyl-L-valine = 5-oxoproline + L-valine
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Product in Enzyme-catalyzed Reactions (6 results)
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5-L-glutamyl-4-nitroanilide + L-Val = 4-nitroaniline + 5-L-glutamyl-L-Val
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5-L-glutamyl-4-nitroanilide + L-valine = 4-nitroaniline + 5-L-glutamyl-L-valine
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L-gamma-glutamyl-4-nitroanilide + L-valine = 4-nitroaniline + 5-L-glutamyl-L-valine
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5-L-glutamyl-4-nitroanilide + Val = 4-nitroaniline + 5-L-glutamyl-Val
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5-L-glutamyl-5-L-glutamyl-L-valine = 5-oxoproline + 5-L-glutamyl-L-valine
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ATP + L-Glu + L-valine = ADP + phosphate + gamma-L-Glu-L-valine
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
References & Links
Literature References (6)
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Characterization of the peptide substrate specificity of glutathionylspermidine synthetase from Crithidia fasciculata
1997
De Craecker, S.; Verbruggen, C.; Rajan, P.; Smith, K.; Haemers, A.; Fairlamb, A.H.
Mol. Biochem. Parasitol.
84
25-32
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gamma-Glutamylcyclotransferase from rat kidney
1981
Meister, A.
Methods Enzymol.
113
428-445
gamma-Glutamyl cyclotransferase from rat kidney. Sulfhydryl groups and isolation of a stable form of the enzyme
1978
Taniguchi, N.; Meister, A.
J. Biol. Chem.
253
1799-1806
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Purification, properties and function of a unique gamma-glutamyl cyclotransferase from the housefly, Musca domestica
1973
Bodnaryk, R.P.; McGirr, L.
Biochim. Biophys. Acta
315
352-362
Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding
2002
Kelly, B.S.; Antholine, W.E.; Griffith, O.W.
J. Biol. Chem.
277
50-58
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Salt-tolerant gamma-glutamyltranspeptidase from Bacillus subtilis 168 with glutaminase activity
2003
Minami, H.; Suzuki, H.; Kumagai, H.
Enzyme Microb. Technol.
32
431-438
Links to other databases for 5-L-glutamyl-L-valine
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