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Ligand 5,6-Dihydroxyindole-2-carboxylate

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.3.3.12

L-dopachrome = 5,6-dihydroxyindole-2-carboxylate

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Product in Enzyme-catalyzed Reactions (2 results)

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Show Product (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.3.3.12

dopachrome = 5,6-dihydroxyindole-2-carboxylate

648804, 648805, 648806, 648807, 648809, 648810, 648811, 648808

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5.3.3.12

L-dopachrome = 5,6-dihydroxyindole-2-carboxylate

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5.3.3.12

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

648804

2106316

Dopachrome conversion factor functions as an isomerase

1990

Pawelek, J.M.

Biochem. Biophys. Res. Commun.

166

1328-1333

648805

2169885

Regulation of mammalian melanogenesis I: partial purification and characterization of a dopachrome converting factor: dopachrome tautomerase

1990

Aroca, P.; Garcia-Borron, J.C.; Solano, F.; Lozano, J.A.

Biochim. Biophys. Acta

1035

266-275

648806

7886003

The mouse brown (b) locus protein functions as a dopachrome tautomerase

1994

Winder, A.J.; Wittbjer, A.; Odh, G.; Rosengren, E.; Rorsman, H.

Pigment Cell Res.

7

305-310

648807

7980602

Dopachrome tautomerase is a zinc-containing enzyme

1994

Solano, F.; Martinez-Liarte, J.H.; Jimenez-Cervantes, C.; Garcia-Borron, J.C.; Lozano, J.A.

Biochem. Biophys. Res. Commun.

204

1243-1250

648808

8192674

A new dopachrome-rearranging enzyme from the ejected ink of the cuttlefish Sepia officinalis

1994

Palumbo, A.; d'Ischia, M.; Misuraca, G.; De Martino, L.; Prota, G.

Biochem. J.

299

839-844

648809

1633843

Evidence that dopachrome tautomerase is a ferrous iron-binding glycoprotein

1992

Chakraborty, A.K.; Orlow, S.J.; Pawelek, J.M.

FEBS Lett.

302

126-128

648810

1537333

A second tyrosine-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase

1992

Tsukamoto, K.; Jackson, I.J.; Urabe, K.; Montague, P.M.; Hearing, V.J.

EMBO J.

11

519-526

648811

1958700

Comparative action of dopachrome tautomerase and metal ions on the rearragement of dopachrome

1991

Palumbo, A.; Solano, F.; Misuraca, G.; Aroca, P.; Borron, J.C.G.; Lozano, J.A.; Prota, G.

Biochim. Biophys. Acta

1115

1-5

Links to other databases for 5,6-Dihydroxyindole-2-carboxylate

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ChEBI

PubChem

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