Ligand decanoyl-[acyl-carrier protein]

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of decanoyl-[acyl-carrier protein] (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C24H44N3O9PR2S
decanoyl-[acyl-carrier protein]
Synonyms:
C10-[acyl-carrier protein], decanoyl-ACP, decanoyl-[acp], decanoyl-[acyl carrier protein]


Show all pahtways known for Show all BRENDA pathways known for decanoyl-[acyl-carrier protein]

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
S-adenosyl-L-methionine + decanoyl-[acyl-carrier protein] = 5'-methylthioadenosine + N-decanoyl-L-homoserine-1,4-lactone + [acyl-carrier protein]
-
show the reaction diagram
decanoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + decanoate
-

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
decanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-decanoyl-N-acetylglucosamine
-
show the reaction diagram
decanoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = ? + CO2 + [acyl-carrier protein]
-
show the reaction diagram
decanoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + decanoate
-

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
2-decenoyl-[acyl-carrier protein] + NADPH = decanoyl-[acyl-carrier protein] + NADP+
-
-
show the reaction diagram
C8-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = C10-[acyl-carrier protein] + CO2 + [acyl-carrier protein]
-
-
show the reaction diagram
ATP + decanoic acid + [acyl-carrier protein] = AMP + diphosphate + decanoyl-[acyl-carrier protein]
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
reversible, noncompetitive inhibition versus malonyl-[acyl-carrier-protein] and uncompetitive versus acetyl-CoA, IC50 is 0.00045 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
pH 6.8, 37°C
551
-
pH 7.5, 37°C, recombinant enzyme
mutant enzyme I198E, at pH 8.0 and 27°C
0.22
-
mutant enzyme K287E, at pH 8.0 and 27°C
0.24
-
wild type enzyme, at pH 8.0 and 27°C
0.33
-

KM Value (12 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
-
0.0133
-
pH 6.8, 37°C
0.0018
-
pH 7.5, 37°C, recombinant enzyme
0.403
-
synthase II
0.0133
-
synthase IV
0.0031
-
-
0.0023
-
medium-chain acyl-ACP thioesterase
0.0031
-
mutant enzyme I198E, at pH 8.0 and 27°C
0.39
-
mutant enzyme K287E, at pH 8.0 and 27°C
0.29
-
oleoyl-ACP thioesterase
0.004
-
wild type enzyme, at pH 8.0 and 27°C
0.13
-
-
0.0023
-

IC50 Value (1 result)

COMMENTARY
EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
LITERATURE
reversible, noncompetitive inhibition versus malonyl-[acyl-carrier-protein] and uncompetitive versus acetyl-CoA, IC50 is 0.00045 mM
0.00045
-

References & Links

Links to other databases for decanoyl-[acyl-carrier protein]

ChEBI
PubChem
-
-