Ligand view of 4-hydroxyphenylglyoxylate (29547 - KXFJZKUFXHWWAJ-UHFFFAOYSA-N)

C₈H₆O₄

4-hydroxyphenylglyoxylate

KXFJZKUFXHWWAJ-UHFFFAOYSA-N

BRENDA

KEGG

Aminobenzoate degradation, Biosynthesis of secondary metabolites, Biosynthesis of vancomycin group antibiotics, Microbial metabolism in diverse environments, Monobactam biosynthesis

MetaCyc

4-hydroxymandelate degradation

2.6.1.72

4-hydroxyphenylglyoxylate + L-glutamate = D-4-hydroxyphenylglycine + 2-oxoglutarate

675793

-

2.6.1.B17

4-hydroxybenzoylformate + L-tyrosine = (2S)-4-hydroxyphenylglycine + 4-hydroxyphenylpyruvate

-

D-4-hydroxyphenylglycine + 2-oxoglutarate = 4-hydroxyphenylglyoxylate + L-glutamate

-

2.6.1.B17

(2S)-4-hydroxyphenylglycine + 4-hydroxyphenylpyruvate = 4-hydroxybenzoylformate + L-tyrosine

-

2.6.1.72

4-hydroxyphenylglyoxylate + L-glutamate = D-4-hydroxyphenylglycine + 2-oxoglutarate

-

4-hydroxy-DL-mandelate + ferricyanide = 2-oxo-2-(4-hydroxyphenyl)acetate + ferrocyanide + H2O

-

1.1.99.B9

(2S)-hydroxy(4-hydroxyphenyl)acetic acid + acceptor = (4-hydroxyphenyl)(oxo)acetic acid + reduced acceptor

-

2.6.1.72

D-4-hydroxyphenylglycine + 2-oxoglutarate = 4-hydroxyphenylglyoxylate + L-glutamate

636992, 636991, -

-

2.6.1.B17

(2S)-4-hydroxyphenylglycine + 4-hydroxyphenylpyruvate = 4-hydroxybenzoylformate + L-tyrosine

-

2.3.1.21

CPT I, greatly reduced inhibition of protease treated enzyme

486572

-

486572

8180250

Hepatic carnitine palmitoyltransferase-I has two independent inhibitory binding sites for regulation of fatty acid oxidation

1994

Kashfi, K.; Mynatt, R.L.; Cook, G.A.

Biochim. Biophys. Acta

1212

245-252

636991

-

DL-4-Hydroxyphenylglycine catabolism in Pseudomonas putida MW27

1988

Van den Tweel, W.J.J.; Widjojoatmodjo, M.N.; de Bont, J.A.M.

Arch. Microbiol.

150

471-476

636992

-

The involvement of an enantioselctive transaminase in the metabolism of D-3- and D-4-hydroxyphenylglycine in Pseudomonas putida LW-4

1988

Van den Tweel, W.J.J.; Smits, J.P.; Ogg, R.L.H.P.; de Bont, J.A.M.

Appl. Microbiol. Biotechnol.

29

224-230

675793

16466681

Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg)

2006

Müller, U.; van Assema, F.; Gunsior, M.; Orf, S.; Kremer, S.; Schipper, D.; Wagemans, A.; Townsend, C.A.; Sonke, T.; Bovenberg, R.; Wubbolts, M.

Metab. Eng.

8

196-208

724727

11137816

Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics

2000

Hubbard, B.K.; Thomas, M.G.; Walsh, C.T.

Chem. Biol.

7

931-942

ChEBI

PubChem

UniChem

Ligand 4-hydroxyphenylglyoxylate

Basic Ligand Information

Related pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

Substrate in Enzyme-catalyzed Reactions (4 results)

Product in Enzyme-catalyzed Reactions (6 results)

Inhibitor in Enzyme-catalyzed Reactions (1 result)

Enzyme Kinetic Parameters

References & Links

Literature References (5)

Links to other databases for 4-hydroxyphenylglyoxylate