Ligand 5beta-Androstan-3alpha-ol-17-one

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Basic Ligand Information

Molecular Structure
Picture of 5beta-Androstan-3alpha-ol-17-one (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H30O2
5beta-Androstan-3alpha-ol-17-one
QGXBDMJGAMFCBF-IINPKOONSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5beta-androstan-3alpha-ol-17-one + NADP+ = (5beta)-androstan-3,17-dione + NADPH + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5beta-androstan-3alpha-ol-17-one + NADPH + H+ = ?
show the reaction diagram
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5beta-androstan-3alpha-ol-17-one + NAD+ = 5beta-androstan-3,17-dione + NADH + H+
show the reaction diagram
-
5beta-androstan-3alpha-ol-17-one + NAD+ = 5beta-androstan-3,17-dione + NADH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5beta-androstan-3alpha,17beta-diol + NAD+ = 5beta-androstan-3alpha-ol-17-one + NADH
show the reaction diagram
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5beta-androstane-3,17-dione + NADPH = 5beta-androstan-3alpha-ol-17-one + NADP+
show the reaction diagram
-
-
5beta-androstane-3,17-dione + NADPH = 5beta-androstan-3alpha-ol-17-one + NADP+
show the reaction diagram
-
5beta-androstane-3,17-dione + NADH = 5beta-androstan-3alpha-ol-17-one + NAD+
show the reaction diagram
-
-
5beta-androstan-3alpha,17beta-diol + NAD+ = 5beta-androstan-3alpha-ol-17-one + NADH
show the reaction diagram
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5beta-androstan-3,17-dione + NADPH + H+ = 5beta-androstan-3alpha-ol-17-one + NADP+
show the reaction diagram
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-
5beta-androstan-3,17-dione + NADPH = 5beta-androstan-3alpha-ol-17-one + NADP+
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.067
-
at pH 7.4 and 37°C
1.33
-
-

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0017
-
at pH 7.4 and 37°C
0.001
-
-
0.0074
-
DD1

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.031
-
DD3

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.0048
-
in 0.1 M potassium phosphate, pH 7.4, at 25°C

References & Links

Links to other databases for 5beta-Androstan-3alpha-ol-17-one

ChEBI
PubChem
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PubChem