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Ligand 6-methylthioguanine
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Basic Ligand Information
2-amino-6-methyl-mercaptopurine, 2-Amino-6-methylthiopurine, 2-amino 6-methylmercaptopurine, 6-methylmercaptoguanine, methylthioguanine
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open all tablesRoles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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EC NUMBER 
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
deoxyadenosine + 2-amino 6-methylmercaptopurine = adenine + 9-(2-deoxy-beta-D-ribofuranosyl)-2-amino-6-methylmercaptopurine
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thymidine + 2-amino-6-methyl-mercaptopurine = thymine + 9-(2-deoxy-beta-D-ribofuranosyl)-2-amino-6-methylmercaptopurine
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Product in Enzyme-catalyzed Reactions (3 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + 2-amino-6-thiopurine = S-adenosyl-L-homocysteine + 2-amino-6-methylthiopurine
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S-adenosyl-L-methionine + 6-thioguanine = S-adenosyl-L-homocysteine + 6-methylthioguanine
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S-adenosyl-L-methionine + thioguanine nucleotide = S-adenosyl-L-homocysteine + methylthioguanine
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Inhibitor in Enzyme-catalyzed Reactions (2 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Enzyme Kinetic Parameters
Ki Value (1 result)
References & Links
Literature References (4)
Links to other databases for 6-methylthioguanine
ChEBI
PubChem
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Release 2023.1 (January 2023)
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