Ligand 16alpha-hydroxyestrone

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Basic Ligand Information

Molecular Structure
Picture of 16alpha-hydroxyestrone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C18H22O3
16alpha-hydroxyestrone
WPOCIZJTELRQMF-QFXBJFAPSA-N
Synonyms:
3,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one, 3,16alpha-dihydroxy-estra-1,3,5(10)-triene-17-one
Pathway Source
Pathways

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3'-phosphoadenylylsulfate + 3,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one = adenosine 3',5'-bisphosphate + 16-alpha-hydroxy-1,3,5(10)-estratrien-17-one 3-sulfate
show the reaction diagram
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16alpha-Hydroxyestrone = 16beta-Hydroxyestrone
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-hydroxy-estra-1,3,5(10)-triene-16,17-dione + NAD(P)H = 3,16alpha-dihydroxy-estra-1,3,5(10)-triene-17-one + NAD(P)H
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
maximum inhibition at 100 nM
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Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.9
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References & Links

Links to other databases for 16alpha-hydroxyestrone

ChEBI
PubChem
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PubChem