Ligand 2-dehydro-D-gluconate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 2-dehydro-D-gluconate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H10O7
2-dehydro-D-gluconate
VBUYCZFBVCCYFD-JJYYJPOSSA-N
Synonyms:
2-keto-D-gluconate, 2-Keto-D-gluconic acid, 2-ketogluconate, 2-oxo-D-gluconate, 2-oxo-gluconate, 2-oxogluconate, alpha-oxogluconate, D-arabino-hex-2-ulosonate

Show all pahtways known for Show all BRENDA pathways known for 2-dehydro-D-gluconate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-D-gluconate + acceptor = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-didehydro-D-gluconate + NADPH + H+ = 2-dehydro-D-gluconate + NADP+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (15 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-D-gluconate + NADPH + H+ = D-gluconate + NADP+
show the reaction diagram
-
2-ketogluconate + NAD(P)H = D-gluconate + NAD(P)+
show the reaction diagram
-
ATP + 2-keto-D-gluconate = ADP + 6-phospho-2-keto-D-gluconate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-didehydro-D-gluconate + NADPH + H+ = 2-dehydro-D-gluconate + NADP+
show the reaction diagram
-
-
D-fucono-1,5-lactone + O2 = 2-keto-D-gluconate + D-araboascorbate + H2O2
show the reaction diagram
-
D-gluconate + acceptor = 2-oxo-gluconate + reduced acceptor
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
48.2
-
pH 7.0, 25°C

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
50
-
reaction with ferricyanide
4.6
-
pH 7.5, 37°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2-dehydro-D-gluconate

ChEBI
PubChem
-
PubChem