Ligand 1-pyrroline-4-hydroxy-2-carboxylate

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Basic Ligand Information

Molecular Structure
Picture of 1-pyrroline-4-hydroxy-2-carboxylate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H7NO3
1-pyrroline-4-hydroxy-2-carboxylate
WFOFKRKDDKGRIK-UHFFFAOYSA-N
Synonyms:
1-pyrroline-3-hydroxy-5-carboxylate, DELTA1-pyrroline-3-hydroxy-5-carboxylate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-pyrroline-4-hydroxy-2-carboxylate + H2O = 2,5-dioxopentanoate + NH3
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
DELTA1-pyrroline-3-hydroxy-5-carboxylate + NAD+ + H2O = 4-hydroxyglutamate + NADH
show the reaction diagram
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1-pyrroline-3-hydroxy-5-carboxylate + NAD(P)H = L-hydroxyproline + NAD(P)+
show the reaction diagram
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1-pyrroline-4-hydroxy-2-carboxylate + H2O = 2,5-dioxopentanoate + NH3
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.19
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at pH 8.0 and 30°C

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4.4
-
-

References & Links

Links to other databases for 1-pyrroline-4-hydroxy-2-carboxylate

ChEBI
PubChem
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PubChem