Ligand 1-phospho-alpha-D-galacturonate
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Basic Ligand Information
Molecular Structure
C6H11O10P
1-phospho-alpha-D-galacturonate
AIQDYKMWENWVQJ-DTEWXJGMSA-N
alpha-D-galacturonate 1-phosphate, alpha-D-galacturonic acid 1-phosphate, D-galacturonate 1-phosphate, D-galacturonic acid 1-phosphate, galacturonic acid 1-phosphate
Show all BRENDA pathways known for 1-phospho-alpha-D-galacturonate
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (2 results)
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ATP + D-galacturonate = ADP + 1-phospho-alpha-D-galacturonate
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UDP-galacturonic acid + diphosphate = galacturonic acid 1-phosphate + UTP
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Substrate in Enzyme-catalyzed Reactions (3 results)
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UTP + alpha-D-galacturonate 1-phosphate = diphosphate + UDP-D-galacturonate
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D-galacturonate 1-phosphate + UTP = UDP-D-galacturonate + diphosphate
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UTP + D-galacturonic acid 1-phosphate = diphosphate + UDP-galacturonic acid
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Product in Enzyme-catalyzed Reactions (6 results)
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ATP + D-galacturonate = ADP + 1-phospho-alpha-D-galacturonate
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ATP + D-galacturonate = ADP + 1-phospho-alpha-D-galacturonate
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D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP
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ATP + D-galacturonic acid = ADP + alpha-D-galacturonic acid 1-phosphate
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ATP + D-galacturonic acid = ADP + D-galacturonic acid 1-phosphate
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UDP-galacturonic acid + diphosphate = galacturonic acid 1-phosphate + UTP
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links
Literature References (4)
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Phosphorylation of D-galacturonic acid by extracts from germinating seeds of Phaseolus aureus
1961
Neufeld, E.F.; Feingold, D.S.; Ilves, S.M.; Kessler, G.; Hassid, W.Z.
J. Biol. Chem.
236
3102-3105
Preparation of UDP-galacturonic acid using UDP-sugar pyrophosphorylase
2006
Ohashi, T.; Cramer, N.; Ishimizu, T.; Hase, S.
Anal. Biochem.
352
182-187
Leishmania UDP-sugar pyrophosphorylase: the missing link in galactose salvage?
2010
Damerow, S.; Lamerz, A.C.; Haselhorst, T.; Fuehring, J.; Zarnovican, P.; von Itzstein, M.; Routier, F.H.
J. Biol. Chem.
285
878-887
Structural basis for the broad substrate range of the UDP-sugar pyrophosphorylase from Leishmania major
2011
Dickmanns, A.; Damerow, S.; Neumann, P.; Schulz, E.C.; Lamerz, A.C.; Routier, F.H.; Ficner, R.
J. Mol. Biol.
405
461-478
Links to other databases for 1-phospho-alpha-D-galacturonate
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