Ligand 1,5-anhydro-D-glucitol

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Basic Ligand Information

Molecular Structure
Picture of 1,5-anhydro-D-glucitol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H12O5
1,5-anhydro-D-glucitol
MPCAJMNYNOGXPB-SLPGGIOYSA-N
Synonyms:
1,5-anhydroglucitol, 1-deoxy-D-glucopyranoside, 1-deoxy-D-glucose, D-1,5-anhydroglucitol

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,5-anhydro-D-fructose + NADPH = 1,5-anhydro-D-glucitol + NADP+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,5-anhydro-D-glucitol + NADPH = ? + NADP+
show the reaction diagram
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1,5-anhydro-D-glucitol + NADP+ = ?
show the reaction diagram
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1,5-anhydro-D-glucitol + acceptor = 1,3,5-dehydro-D-glucitol + reduced acceptor
show the reaction diagram
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1,5-anhydro-D-glucitol + 2,6-dichlorophenolindophenol = ? + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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1,5-anhydro-D-glucitol + beta-D-glucose 1-phosphate = 1,5-anhydro-4-O-alpha-D-glucopyranosyl-D-glucitol + phosphate
show the reaction diagram
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ATP + 1,5-anhydro-D-glucitol = ADP + 1,5-anhydro-D-glucitol 6-phosphate
show the reaction diagram
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D-1,5-anhydroglucitol + ADP = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-deoxy-D-glucitol + NADP+ = 1-deoxy-D-glucose + NADPH
show the reaction diagram
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1,5-anhydro-D-fructose + NADPH = 1,5-anhydro-D-glucitol + NADP+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
2.3% inhibition at 100 mM
-
slight inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (25 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (8 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
76.7
-
pH 7.0, 37C
14.1
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at pH 8.5 and 40C
20.7
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apparent value, pH 6.5, 37C, synthetic reaction, cosubstrate alpha-D-mannose 1-phosphate
1.12
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pH 8.0, 37C

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
10.7
-
pH 7.0, 37C
97.5
-
at pH 8.5 and 40C
79.2
-
apparent value, pH 6.5, 37C, synthetic reaction, cosubstrate alpha-D-mannose 1-phosphate
14.1
-
pH 8.0, 37C
20
-
at 37C, pH 7.4

References & Links

Links to other databases for 1,5-anhydro-D-glucitol

ChEBI
PubChem
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PubChem