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BRENDA support

Ligand propane-1,3-diol

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Basic Ligand Information

Molecular Structure
Picture of propane-1,3-diol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H8O2
propane-1,3-diol
YPFDHNVEDLHUCE-UHFFFAOYSA-N
Synonyms:
1,3-propandiol, 1,3-Propanediol, 2-deoxyglycerol, Propan-1,3-diol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (29 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,3-propanediol + 2 NAD+ + H2O = ? + 2 NADH + 2 H+
show the reaction diagram
-
1,3-propandiol + NAD+ = ? + NADH + H+
show the reaction diagram
-
propane-1,3-diol + NAD+ = ? + NADH
show the reaction diagram
-
propane-1,3-diol + NAD+ = ?
show the reaction diagram
-
1,3-propanediol + NAD+ = ?
show the reaction diagram
-
1,3-propanediol + NAD+ = ? + NADH + H+
show the reaction diagram
-
propan-1,3-diol + NAD+ = ?
show the reaction diagram
-
1,3-propanediol + ferricytochrome c = ?
show the reaction diagram
-
1,3-propanediol + acceptor = ? + reduced acceptor
show the reaction diagram
-
1,3-propanediol + O2 = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-hydroxypropionaldehyde + NADH = propan-1,3-diol + NAD+
show the reaction diagram
-
3-hydroxypropionaldehyde + NADPH + H+ = propan-1,3-diol + NADP+
show the reaction diagram
-
[(3-[(3-hydroxypropoxy)carbonyl]-5-[[3-([4-[(3-hydroxypropoxy)carbonyl]benzoyl]oxy)propoxy]carbonyl]phenyl)-lambda4-sulfanetriyl]tris(oxidanide) + H2O = terephthalic acid + 5-sulfoisophthalic acid + 1,3-propanediol
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates
-
activates
-
isoform AC6 shows about 17% stimulation of activity with 100 mM 1,3-propanediol, isoform AC7 shows about 20% stimulation of activity with 100 mM 1,3-propanediol, isoform AC9 shows about 17% stimulation of activity with 100 mM 1,3-propanediol
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor versus glycerol in direction of glycerol oxidation, noncompetitive inhibitor versus NAD+, competitive inhibitor versus dihydroxyacetone in direction of glycerol reduction, noncompetitive inhibitor versus NADH
-

3D Structure of Enzyme-Ligand-Complex (PDB) (80 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.041
-
pH 7.5, 23°C
9.98
-
pH 9.0, 55°C

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
88
-
-

References & Links

Links to other databases for propane-1,3-diol

ChEBI
PubChem
ChEBI
PubChem