Ligand (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate

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Basic Ligand Information

Molecular Structure
Picture of (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O7
(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate
GJQWCDSAOUMKSE-STHAYSLISA-N
Synonyms:
2,3-diketo-L-gulonate, 2,3-diketo-L-gulonic acid, 2,3-dioxo-L-gulonate


Show all pahtways known for Show all BRENDA pathways known for (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H = 3-dehydro-L-gulonate + NAD(P)+
show the reaction diagram
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2,3-Diketo-L-gulonic acid = ?
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H = 3-dehydro-L-gulonate + NAD(P)+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-keto-L-gulonate + NADH = 2,3-diketo-L-gulonate + NAD+
show the reaction diagram
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Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.16
-
-
7.3
-
cofactor NADH, pH 6.3

References & Links

Links to other databases for (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate

ChEBI
PubChem
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PubChem