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Ligand dTDP-beta-L-mycarose

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for dTDP-beta-L-mycarose

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

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Show Natural Substrate (3 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.1.318

dTDP-beta-L-mycarose + demethyllactenocin = dTDP + demethylmacrocin

725892

-

2.4.1.328

dTDP-beta-L-mycarose + erythronolide B = dTDP + 3-alpha-L-mycarosylerythronolide B

716130, 730081

-

2.4.1.328

dTDP-beta-L-mycarose + erythronolide B = dTDP + 3-beta-L-mycarosylerythronolide B

724765

-

2.4.1.328

2 entries

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

2.4.1.277

dTDP-beta-L-mycarose + erythronolide B = dTDP + 3-alpha-L-mycarosylerythronolide B

735516

-

2.4.1.318

dTDP-beta-L-mycarose + demethyllactenocin = dTDP + demethylmacrocin

725892

-

2.4.1.328

dTDP-beta-L-mycarose + erythronolide B = dTDP + 3-alpha-L-mycarosylerythronolide B

716130, 730081, 735516

-

2.4.1.328

dTDP-beta-L-mycarose + erythronolide B = dTDP + 3-beta-L-mycarosylerythronolide B

724765

-

2.4.1.328

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (5)

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Show Reference (5 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

716130

9353926

Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production

1997

Summers, R.G.; Donadio, S.; Staver, M.J.; Wendt-Pienkowski, E.; Hutchinson, C.R., Katz, L.

Microbiology

143

3251-3262

724765

17262863

The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification

2007

Zhang, C.; Fu, Q.; Albermann, C.; Li, L.; Thorson, J.S.

Chembiochem

8

385-390

725892

10658660

The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin

2000

Bate, N.; Butler, A.R.; Smith, I.P.; Cundliffe, E.

Microbiology

146

139-146

730081

18430483

Combinatorial biosynthesis of 5-O-desosaminyl erythronolide A as a potent precursor of ketolide antibiotics

2008

Basnet, D.B.; Park, J.W.; Yoon, Y.J.

J. Biotechnol.

135

92-96

735516

26552796

In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea

2016

Wu, H.; Li, W.; Xin, C.; Zhang, C.; Wang, Y.; Ren, S.; Ren, M.; Zhao, W.; Yuan, L.; Xu, Z.; Yuan, H.; Geng, M.; Zhang, L.; Weaver, D.T.; Zhang, B.

Appl. Microbiol. Biotechnol.

100

2257-2266

Links to other databases for dTDP-beta-L-mycarose

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Show Links (1 entry)

ChEBI

PubChem